Dendrimers have attracted great interest for the design of functional materials. Because the core porphyrin unit in dendrimer porphyrin (DP) is surrounded by large poly(benzyl ether) dendritic wedges with ionic peripheries, the resulting electrostatic interaction with oppositely charged polymeric materials has been used to create various functional nano-devices. In this paper, we briefly review DP-based self-assembled biomedical nano-devices, including DP-loaded polyion complex micelles, the ternary complex systems used for gene delivery, polymer-metal complex micelles, the hollow nanocapsules used for combination cancer therapy, and the DP-immobilized surfaces used for diagnostic tools.
Bibliographical noteFunding Information:
This work was supported by a National Research Foundation (NRF) grant funded by the Korean government (MEST) (no. 2011-0001126). Y.-H. Jeong and H.-J. Yoon acknowledge fellowships from the BK21 program supported by MEST, Korea.
All Science Journal Classification (ASJC) codes
- Polymers and Plastics
- Materials Chemistry