Dendron-mediated self-assembly of highly PEGylated block copolymers: A modular nanocarrier platform

Jin Woo Bae; Ryan M. Pearson; Niladri Patra; Suhair Sunoqrot; Lela Vuković; Petr Král; Seungpyo Hong

doi:10.1039/c1cc14331j

Dendron-mediated self-assembly of highly PEGylated block copolymers: A modular nanocarrier platform

Jin Woo Bae, Ryan M. Pearson, Niladri Patra, Suhair Sunoqrot, Lela Vuković, Petr Král, Seungpyo Hong

Department of Pharmacy

Research output: Contribution to journal › Article

37 Citations (Scopus)

Abstract

PEGylated dendron coils (PDCs) were investigated as a novel potential nanocarrier platform. PDCs self-assembled into micelles at lower CMCs than linear copolymer counterparts by 1-2 orders of magnitude, due to the unique architecture of dendrons. MD simulations also supported thermodynamically favourable self-assembly mediated by dendrons.

Original language	English
Pages (from-to)	10302-10304
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	37
DOIs	https://doi.org/10.1039/c1cc14331j
Publication status	Published - 2011 Oct 7

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All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Cite this

Bae, J. W., Pearson, R. M., Patra, N., Sunoqrot, S., Vuković, L., Král, P., & Hong, S. (2011). Dendron-mediated self-assembly of highly PEGylated block copolymers: A modular nanocarrier platform. Chemical Communications, 47(37), 10302-10304. https://doi.org/10.1039/c1cc14331j

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10.1039/c1cc14331j