Dendron-mediated self-assembly of highly PEGylated block copolymers: A modular nanocarrier platform

Jin Woo Bae; Ryan M. Pearson; Niladri Patra; Suhair Sunoqrot; Lela Vuković; Petr Král; Seungpyo Hong

doi:10.1039/c1cc14331j

Dendron-mediated self-assembly of highly PEGylated block copolymers: A modular nanocarrier platform

Jin Woo Bae, Ryan M. Pearson, Niladri Patra, Suhair Sunoqrot, Lela Vuković, Petr Král, Seungpyo Hong

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

Abstract

PEGylated dendron coils (PDCs) were investigated as a novel potential nanocarrier platform. PDCs self-assembled into micelles at lower CMCs than linear copolymer counterparts by 1-2 orders of magnitude, due to the unique architecture of dendrons. MD simulations also supported thermodynamically favourable self-assembly mediated by dendrons.

Original language	English
Pages (from-to)	10302-10304
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	37
DOIs	https://doi.org/10.1039/c1cc14331j
Publication status	Published - 2011 Oct 7

All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/c1cc14331j

Cite this

@article{bd3b223fcf854f428218bff3c0f92c2b,

title = "Dendron-mediated self-assembly of highly PEGylated block copolymers: A modular nanocarrier platform",

abstract = "PEGylated dendron coils (PDCs) were investigated as a novel potential nanocarrier platform. PDCs self-assembled into micelles at lower CMCs than linear copolymer counterparts by 1-2 orders of magnitude, due to the unique architecture of dendrons. MD simulations also supported thermodynamically favourable self-assembly mediated by dendrons.",

author = "Bae, {Jin Woo} and Pearson, {Ryan M.} and Niladri Patra and Suhair Sunoqrot and Lela Vukovi{\'c} and Petr Kr{\'a}l and Seungpyo Hong",

year = "2011",

month = oct,

day = "7",

doi = "10.1039/c1cc14331j",

language = "English",

volume = "47",

pages = "10302--10304",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "37",

}

TY - JOUR

T1 - Dendron-mediated self-assembly of highly PEGylated block copolymers

T2 - A modular nanocarrier platform

AU - Bae, Jin Woo

AU - Pearson, Ryan M.

AU - Patra, Niladri

AU - Sunoqrot, Suhair

AU - Vuković, Lela

AU - Král, Petr

AU - Hong, Seungpyo

PY - 2011/10/7

Y1 - 2011/10/7

N2 - PEGylated dendron coils (PDCs) were investigated as a novel potential nanocarrier platform. PDCs self-assembled into micelles at lower CMCs than linear copolymer counterparts by 1-2 orders of magnitude, due to the unique architecture of dendrons. MD simulations also supported thermodynamically favourable self-assembly mediated by dendrons.

AB - PEGylated dendron coils (PDCs) were investigated as a novel potential nanocarrier platform. PDCs self-assembled into micelles at lower CMCs than linear copolymer counterparts by 1-2 orders of magnitude, due to the unique architecture of dendrons. MD simulations also supported thermodynamically favourable self-assembly mediated by dendrons.

UR - http://www.scopus.com/inward/record.url?scp=80052541473&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80052541473&partnerID=8YFLogxK

U2 - 10.1039/c1cc14331j

DO - 10.1039/c1cc14331j

M3 - Article

C2 - 21858356

AN - SCOPUS:80052541473

VL - 47

SP - 10302

EP - 10304

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 37

ER -

Dendron-mediated self-assembly of highly PEGylated block copolymers: A modular nanocarrier platform

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this