Design and biological evaluation of novel antioxidants containing N-t-Butyl-N-hydroxylaminophenyl moieties

Kyung Mi Kim, Kyung Hwa Kim, Tae Cheon Kang, Won Yeon Kim, Myung Ryul Lee, Hyuk Jun Jung, In Koo Hwang, Sung Bo Ko, Jae Young Koh, Moo Ho Won, Eu Gene Oh, Injae Shin

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Abstract

In order to develop therapeutic agents against neurodegenerative diseases, we designed novel antioxidants containing N-t-butyl-N-hydroxylaminophenyl moieties and evaluated in vitro and in vivo neuroprotective properties as well as anti-ischemic effects.

Original languageEnglish
Pages (from-to)2273-2275
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Volume13
Issue number14
DOIs
Publication statusPublished - 2003 Jul 21

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All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

Cite this

Kim, K. M., Kim, K. H., Kang, T. C., Kim, W. Y., Lee, M. R., Jung, H. J., Hwang, I. K., Ko, S. B., Koh, J. Y., Won, M. H., Oh, E. G., & Shin, I. (2003). Design and biological evaluation of novel antioxidants containing N-t-Butyl-N-hydroxylaminophenyl moieties. Bioorganic and Medicinal Chemistry Letters, 13(14), 2273-2275. https://doi.org/10.1016/S0960-894X(03)00444-X