Design and synthesis of biofunctionalized metallic/magnetic nanomaterials

Eun Kyung Lim, Seungjoo Haam, Kwangyeol Lee, yongmin Huh

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

Organic solvent-soluble nanocrystals suitable for magnetic resonance imaging are prepared by two routes, namely, a coprecipitation method and a multiple-step thermal decomposition method (seed-mediated growth). The size, shape, crystallinity, phase, and composition of the prepared nanocrystals are determined by various characterization techniques, including transmission electron microscopy, vibratingsample magnetometer, X-ray diffraction, and inductively coupled plasma mass spectroscopy. Subsequently, the organic-soluble nanocrystals are rendered water-soluble by two methods, the microemulsion method and the ligand exchange method, for biomedical applications. Detailed protocols for the preparation of water-soluble nanocrystals, as well as procedures for drug-loading and antibody conjugation to the water-soluble nanocrystals are provided.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages583-595
Number of pages13
Volume751
DOIs
Publication statusPublished - 2011 Jan 1

Publication series

NameMethods in Molecular Biology
Volume751
ISSN (Print)1064-3745

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Nanostructures
Nanoparticles
Water
Transmission Electron Microscopy
X-Ray Diffraction
Mass Spectrometry
Seeds
Hot Temperature
Magnetic Resonance Imaging
Ligands
Antibodies
Growth
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics

Cite this

Lim, E. K., Haam, S., Lee, K., & Huh, Y. (2011). Design and synthesis of biofunctionalized metallic/magnetic nanomaterials. In Methods in Molecular Biology (Vol. 751, pp. 583-595). (Methods in Molecular Biology; Vol. 751). Humana Press Inc.. https://doi.org/10.1007/978-1-61779-151-2_36
Lim, Eun Kyung ; Haam, Seungjoo ; Lee, Kwangyeol ; Huh, yongmin. / Design and synthesis of biofunctionalized metallic/magnetic nanomaterials. Methods in Molecular Biology. Vol. 751 Humana Press Inc., 2011. pp. 583-595 (Methods in Molecular Biology).
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Lim, EK, Haam, S, Lee, K & Huh, Y 2011, Design and synthesis of biofunctionalized metallic/magnetic nanomaterials. in Methods in Molecular Biology. vol. 751, Methods in Molecular Biology, vol. 751, Humana Press Inc., pp. 583-595. https://doi.org/10.1007/978-1-61779-151-2_36

Design and synthesis of biofunctionalized metallic/magnetic nanomaterials. / Lim, Eun Kyung; Haam, Seungjoo; Lee, Kwangyeol; Huh, yongmin.

Methods in Molecular Biology. Vol. 751 Humana Press Inc., 2011. p. 583-595 (Methods in Molecular Biology; Vol. 751).

Research output: Chapter in Book/Report/Conference proceedingChapter

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Lim EK, Haam S, Lee K, Huh Y. Design and synthesis of biofunctionalized metallic/magnetic nanomaterials. In Methods in Molecular Biology. Vol. 751. Humana Press Inc. 2011. p. 583-595. (Methods in Molecular Biology). https://doi.org/10.1007/978-1-61779-151-2_36