Design methodology for a confocal imaging system using an objective microlens array with an increased working distance

Woojae Choi, Ryung Shin, Jiseok Lim, Shinill Kang

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

In this study, a design methodology for a multi-optical probe confocal imaging system was developed. To develop an imaging system that has the required resolving power and imaging area, this study focused on a design methodology to create a scalable and easy-to-implement confocal imaging system. This system overcomes the limitations of the optical complexities of conventional multi-optical probe confocal imaging systems and the short working distance using a micro-objective lens module composed of two microlens arrays and a telecentric relay optical system. The micro-objective lens module was fabricated on a glass substrate using backside alignment photolithography and thermal reflow processes. To test the feasibility of the developed methodology, an optical system with a resolution of 1 μm/pixel using multi-optical probes with an array size of 10 × 10 was designed and constructed. The developed system provides a 1 mm × 1 mm field of view and a sample scanning range of 100 μm. The optical resolution was evaluated by conducting sample tests using a knife-edge detecting method. The measured lateral resolution of the system was 0.98 μm.

Original languageEnglish
Article number33278
JournalScientific reports
Volume6
DOIs
Publication statusPublished - 2016 Sep 12

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methodology
optical relay systems
probes
modules
lenses
photolithography
field of view
pixels
alignment
conduction
scanning
glass

All Science Journal Classification (ASJC) codes

  • General

Cite this

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abstract = "In this study, a design methodology for a multi-optical probe confocal imaging system was developed. To develop an imaging system that has the required resolving power and imaging area, this study focused on a design methodology to create a scalable and easy-to-implement confocal imaging system. This system overcomes the limitations of the optical complexities of conventional multi-optical probe confocal imaging systems and the short working distance using a micro-objective lens module composed of two microlens arrays and a telecentric relay optical system. The micro-objective lens module was fabricated on a glass substrate using backside alignment photolithography and thermal reflow processes. To test the feasibility of the developed methodology, an optical system with a resolution of 1 μm/pixel using multi-optical probes with an array size of 10 × 10 was designed and constructed. The developed system provides a 1 mm × 1 mm field of view and a sample scanning range of 100 μm. The optical resolution was evaluated by conducting sample tests using a knife-edge detecting method. The measured lateral resolution of the system was 0.98 μm.",
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Design methodology for a confocal imaging system using an objective microlens array with an increased working distance. / Choi, Woojae; Shin, Ryung; Lim, Jiseok; Kang, Shinill.

In: Scientific reports, Vol. 6, 33278, 12.09.2016.

Research output: Contribution to journalArticle

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