Design, total chemical synthesis, and X-ray structure of a protein having a novel linear-loop polypeptide chain topology

Kalyaneswar Mandal, Brad L. Pentelute, Duhee Bang, Zachary P. Gates, Vladimir Yu Torbeev, Stephen B.H. Kent

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Lassoed at the other end: Original synthetic and structure determination methods were used to make a protein molecule with an unprecedented linear-loop polypeptide chain topology, and to characterize its X-ray structure.

Original languageEnglish
Pages (from-to)1481-1486
Number of pages6
JournalAngewandte Chemie - International Edition
Volume51
Issue number6
DOIs
Publication statusPublished - 2012 Feb 6

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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