Detection of infectious viruses and disease biomarkers is of utmost importance in clinical screening for effective identification and treatment of diseases. We demonstrate here the use of liposome rupture impact voltammetry for the qualitative detection of model amphipathic viral peptide on a screen-printed electrode. This novel, proof-of-concept method was proposed for the quick and reliable detection of viruses by nonfaradaic liposome rupture impact voltammetry with the aid of 1,2-dioleoyl-sn-glycero-3-phosphocholine liposomes. This provides an avenue for the development of future on-site, point-of-care detection devices for medical and biological applications.
Bibliographical noteFunding Information:
M.P. acknowledges support from Tier 1 (99/13) from Singapore Ministry of Education. We thank J.A.J and N.-J. C. for providing the DOPC liposomes and AH peptide for the project.
© 2017 American Chemical Society.
All Science Journal Classification (ASJC) codes
- Analytical Chemistry