Determinants of coronary blood flow following primary angioplasty for acute myocardial infarction

Cheol Whan Lee, Myeong Ki Hong, Hyun Sook Kim, Kyoung Suk Rhee, Jae Joong Kim, Seong Wook Park, Seung Jung Park

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The aim of this study was to evaluate determinants of coronary blood flow following primary angioplasty (PA) in acute myocardial infarction (AMI). The corrected TJMI (thrombolysis in myocardial infarction) frame count and the TIMI flow grade were used as indexes of coronary blood flow, and its determinants were examined in 115 consecutive AMI patients who underwent PA (pain onset ≤ 12 hr). The following were validated as univariate predictors of slower corrected TIMI frame count: A lower pressure-derived farctional collateral flow (PDCF) index (P < 0.01), poor angiographic collaterals (P < 0.01), TIMI flow 0, 1 before PA (P < 0.05), and the presence of heavy thrombi (P < 0.01). The PDCF index and the presence of heavy thrombi were independent predictors of i he corrected TIMI frame count. Likewise, the PDCF index (X2 = 12.9; P < 0.01) and the presence of heavy thombi (X2 = 11.4; P < 0.01) were independent predictors of TIMI 3 flow. In conclusion, collateral flow and the presence of thrombi are major determinants of coronary blood flow after PA in AMI. (C) 2000 Wiley-Liss, Inc.

Original languageEnglish
Pages (from-to)402-406
Number of pages5
JournalCatheterization and Cardiovascular Interventions
Volume51
Issue number4
DOIs
Publication statusPublished - 2000 Dec 14

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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