Background: To measure the absorbed dose rate to water and penumbra of a Gamma Knife® (GK) using a polymethyl metacrylate (PMMA) phantom. Methods: A multi-purpose PMMA phantom was developed to measure the absorbed dose rate to water and the dose distribution of a GK. The phantom consists of a hemispherical outer phantom, one exchangeable cylindrical chamber-hosting inner phantom, and two film-hosting inner phantoms. The radius of the phantom was determined considering the electron density of the PMMA such that it corresponds to 8 g/cm 2 water depth, which is the reference depth of the absorbed dose measurement of GK. The absorbed dose rate to water was measured with a PTW TN31010 chamber, and the dose distributions were measured with radiochromic films at the calibration center of a patient positioning system of a GK Perfexion. A spherical water-filled phantom with the same water equivalent depth was constructed as a reference phantom. The dose rate to water and dose distributions at the center of a circular field delimited by a 16-mm collimator were measured with the PMMA phantom at six GK Perfexion sites. Results: The radius of the PMMA phantom was determined to be 6.93 cm, corresponding to equivalent water depth of 8 g/cm 2 . The absorbed dose rate to water was measured with the PMMA phantom, the spherical water-filled phantom and a commercial solid water phantom. The measured dose rate with the PMMA phantom was 1.2% and 1.8% higher than those measured with the spherical water-filled phantom and the solid water phantom, respectively. These differences can be explained by the scattered photon contribution of PMMA off incoming 60 Co gamma-rays to the dose rate. The average full width half maximum and penumbra values measured with the PMMA phantom showed reasonable agreement with two calculated values, one at the center of the PMMA phantom (LGP6.93) and other at the center of a water sphere with a radius of 8 cm (LGP8.0) given by Leksell Gamma Plan using the TMR10 algorithm. Conclusions: A PMMA phantom constructed in this study to measure the absorbed dose rates to water and dose distributions of a GK represents an acceptable and practical alternative for GK dosimetry considering its cost-effectiveness and ease of handling.
Bibliographical noteFunding Information:
This study was supported by the Ministry of Science and ICT (contract number: 2015M2A2A4A02044791) and by the Korea Agency for Technology and Standards (grant number: 10069168).
This work was supported by the research project ‘Development of absolute measurement technology of absorbed dose to water for radiotherapy radiation using micron-size water calorimeter’ with contract number 2015M2A2A4A02044791 granted by the Ministry of Science and ICT (MSIT). This study was also supported by the research project ‘Standardization of accurate measurement technology for determining absorbed dose to water of Gamma Knife radiosurgery facility’ with grant number 10069168 by the Korea Agency for Technology and Standards.
© 2018 The Author(s).
All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging