Development of a transparent, non-cytotoxic, silver ion-exchanged glass with antimicrobial activity and low ion elution

Gyu In Shim, Seong Hwan Kim, Hyung Woo Eom, Kwangmahn Kim, Se Young Choi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We investigated the antimicrobial, cytotoxicity, skin irritation, and ion elution behaviors of glass doped with silver ions with respect to its application to electronic equipment such as phones and tablet screens. The microbes tested were Escherichia coli, Staphylococcus aureus, and Penicillium funiculosum. AgNO3 powder was spread on both sides of aluminosilicate glass, and it was heated to 250-280°C for 10min. Under optimized heating conditions (260°C, 10min), the antimicrobial activity of ion-exchanged glass against bacteria and fungi was over 99.9% after 24 weeks. The glass failed to irritate the skin of experimental animals and was considered non-cytotoxic. The maximum amount of Ag ions that were eluted from the ion-exchanged glass into drinking water was measured at 0.037±0.003μgL-1, an amount which is several orders of magnitude below the standard limit of 0.1mgL-1 in drinking water. Ag ion-exchanged glass had characteristics suitable for use as a display screen, such as a light transmittance of 90% and a surface roughness of 0.704nm. Our findings suggest that glass doped with silver ions is more hygienic than non-doped glass is, and should be applied to display screens and glassware.

Original languageEnglish
Pages (from-to)65-71
Number of pages7
JournalEnzyme and Microbial Technology
Volume72
DOIs
Publication statusPublished - 2015 May 1

Fingerprint

Silver
Glass
Ions
Potable water
Drinking Water
Skin
Penicillium
Aluminosilicates
Cytotoxicity
Fungi
Powders
Heating
Escherichia coli
Tablets
Staphylococcus aureus
Bacteria
Animals
Electronic equipment
Surface roughness
Display devices

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Biochemistry
  • Applied Microbiology and Biotechnology

Cite this

@article{814bb7ce2e5a4cc69255dfd3afb8abcc,
title = "Development of a transparent, non-cytotoxic, silver ion-exchanged glass with antimicrobial activity and low ion elution",
abstract = "We investigated the antimicrobial, cytotoxicity, skin irritation, and ion elution behaviors of glass doped with silver ions with respect to its application to electronic equipment such as phones and tablet screens. The microbes tested were Escherichia coli, Staphylococcus aureus, and Penicillium funiculosum. AgNO3 powder was spread on both sides of aluminosilicate glass, and it was heated to 250-280°C for 10min. Under optimized heating conditions (260°C, 10min), the antimicrobial activity of ion-exchanged glass against bacteria and fungi was over 99.9{\%} after 24 weeks. The glass failed to irritate the skin of experimental animals and was considered non-cytotoxic. The maximum amount of Ag ions that were eluted from the ion-exchanged glass into drinking water was measured at 0.037±0.003μgL-1, an amount which is several orders of magnitude below the standard limit of 0.1mgL-1 in drinking water. Ag ion-exchanged glass had characteristics suitable for use as a display screen, such as a light transmittance of 90{\%} and a surface roughness of 0.704nm. Our findings suggest that glass doped with silver ions is more hygienic than non-doped glass is, and should be applied to display screens and glassware.",
author = "Shim, {Gyu In} and Kim, {Seong Hwan} and Eom, {Hyung Woo} and Kwangmahn Kim and Choi, {Se Young}",
year = "2015",
month = "5",
day = "1",
doi = "10.1016/j.enzmictec.2015.02.008",
language = "English",
volume = "72",
pages = "65--71",
journal = "Enzyme and Microbial Technology",
issn = "0141-0229",
publisher = "Elsevier Inc.",

}

Development of a transparent, non-cytotoxic, silver ion-exchanged glass with antimicrobial activity and low ion elution. / Shim, Gyu In; Kim, Seong Hwan; Eom, Hyung Woo; Kim, Kwangmahn; Choi, Se Young.

In: Enzyme and Microbial Technology, Vol. 72, 01.05.2015, p. 65-71.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Development of a transparent, non-cytotoxic, silver ion-exchanged glass with antimicrobial activity and low ion elution

AU - Shim, Gyu In

AU - Kim, Seong Hwan

AU - Eom, Hyung Woo

AU - Kim, Kwangmahn

AU - Choi, Se Young

PY - 2015/5/1

Y1 - 2015/5/1

N2 - We investigated the antimicrobial, cytotoxicity, skin irritation, and ion elution behaviors of glass doped with silver ions with respect to its application to electronic equipment such as phones and tablet screens. The microbes tested were Escherichia coli, Staphylococcus aureus, and Penicillium funiculosum. AgNO3 powder was spread on both sides of aluminosilicate glass, and it was heated to 250-280°C for 10min. Under optimized heating conditions (260°C, 10min), the antimicrobial activity of ion-exchanged glass against bacteria and fungi was over 99.9% after 24 weeks. The glass failed to irritate the skin of experimental animals and was considered non-cytotoxic. The maximum amount of Ag ions that were eluted from the ion-exchanged glass into drinking water was measured at 0.037±0.003μgL-1, an amount which is several orders of magnitude below the standard limit of 0.1mgL-1 in drinking water. Ag ion-exchanged glass had characteristics suitable for use as a display screen, such as a light transmittance of 90% and a surface roughness of 0.704nm. Our findings suggest that glass doped with silver ions is more hygienic than non-doped glass is, and should be applied to display screens and glassware.

AB - We investigated the antimicrobial, cytotoxicity, skin irritation, and ion elution behaviors of glass doped with silver ions with respect to its application to electronic equipment such as phones and tablet screens. The microbes tested were Escherichia coli, Staphylococcus aureus, and Penicillium funiculosum. AgNO3 powder was spread on both sides of aluminosilicate glass, and it was heated to 250-280°C for 10min. Under optimized heating conditions (260°C, 10min), the antimicrobial activity of ion-exchanged glass against bacteria and fungi was over 99.9% after 24 weeks. The glass failed to irritate the skin of experimental animals and was considered non-cytotoxic. The maximum amount of Ag ions that were eluted from the ion-exchanged glass into drinking water was measured at 0.037±0.003μgL-1, an amount which is several orders of magnitude below the standard limit of 0.1mgL-1 in drinking water. Ag ion-exchanged glass had characteristics suitable for use as a display screen, such as a light transmittance of 90% and a surface roughness of 0.704nm. Our findings suggest that glass doped with silver ions is more hygienic than non-doped glass is, and should be applied to display screens and glassware.

UR - http://www.scopus.com/inward/record.url?scp=84924984838&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84924984838&partnerID=8YFLogxK

U2 - 10.1016/j.enzmictec.2015.02.008

DO - 10.1016/j.enzmictec.2015.02.008

M3 - Article

C2 - 25837509

AN - SCOPUS:84924984838

VL - 72

SP - 65

EP - 71

JO - Enzyme and Microbial Technology

JF - Enzyme and Microbial Technology

SN - 0141-0229

ER -