Development of evidence-based consensus on critical issues in the management of patients with vitiligo: A modified Delphi study

Jung Min Bae, Ki Heon Jeong, Chong Won Choi, Ji Hun Park, Hee Jung Lee, Hee Jung Kim, Sang Hoon Lee, Sang Ho Oh, Jeonghyun Shin, Hee Young Kang, Weon Ju Lee, Hyun Jeong Ju, Dong Hyun Kim, Sung Eun Chang, Dong Youn Lee, You Chan Kim, Gwang Seong Choi, Ki Ho Kim, Tae Heung Kim, Seung Chul LeeAi Young Lee, Seung Kyung Hann, Mu Hyoung Lee, Chul Jong Park

Research output: Contribution to journalArticlepeer-review

Abstract

Background/purpose: Vitiligo remains a major challenge in dermatology. However, much of the treatment remains unclear, because little evidence is available. We sought to answer some critical questions pertaining to management of vitiligo patients. Methods: A modified Delphi process among 31 vitiligo experts was conducted. A total of 12 clinical vitiligo treatment questions without clear answers were collected via a vote. To address each question, two members performed systematic literature reviews and prepared draft statements along with the levels of evidence and strength of recommendation. After reviewing the draft, all expressed their extent of agreement from 1 (strong disagreement) to 9 (strong agreement) for each item. The drafts were revised to reflect suggested comments. Discussion continued until all members agreed with the ultimate decision. Results: The consensus process was completed after five rounds. We identified the best answers to 12 key questions, including issues on long-term phototherapy, systemic and topical corticosteroids, topical calcineurin inhibitors, immunosuppressants, excimer laser treatment, and surgical interventions. Conclusion: This consensus would complement current guidelines and aid both physician and patient decision-making in the treatment of vitiligo.

Original languageEnglish
Pages (from-to)3-11
Number of pages9
JournalPhotodermatology Photoimmunology and Photomedicine
Volume37
Issue number1
DOIs
Publication statusPublished - 2021 Jan

Bibliographical note

Funding Information:
This study was supported by the Research Grant of the Korean Dermatological Association.

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Radiology Nuclear Medicine and imaging
  • Dermatology

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