Development of Korean standard brain templates

Sung Lee Jae; Soo Lee Dong; Jinsu Kim; Kyeong Kim Yu; Eunjoo Kang; Hyejin Kang; Wook Kang Keon; Min Lee Jong; Jae Jin Kim; Hae Jeong Park; Soo Kwon Jun; I. Kim Sun; Woo Yoo Tae; Kee Hyun Chang; Chul Lee Myung

doi:10.3346/jkms.2005.20.3.483

Development of Korean standard brain templates

Sung Lee Jae, Soo Lee Dong, Jinsu Kim, Kyeong Kim Yu, Eunjoo Kang, Hyejin Kang, Wook Kang Keon, Min Lee Jong, Jae Jin Kim, Hae Jeong Park, Soo Kwon Jun, I. Kim Sun, Woo Yoo Tae, Kee Hyun Chang, Chul Lee Myung

Department of Psychiatry

Research output: Contribution to journal › Article › peer-review

57 Citations (Scopus)

Abstract

We developed age, gender and ethnic specific brain templates based on MR and Positron-Emission Tomography (PET) images of Korean normal volunteers. Seventy-eight normal right-handed volunteers (M/F=49/29) underwent 3D T1-weighted SPGR MR and F-18-FDG PET scans. For the generation of standard templates, an optimal target brain that has the average global hemispheric shape was selected for each gender. MR images were then spatially normalized by linear transformation to the target brains, and normalization parameters were reapplied to PET images. Subjects were subdivided into 2 groups for each gender: the young/midlife (<55 yr) and the elderly groups. Young and elderly MRI/PET templates were composed by averaging the spatially normalized images. Korean templates showed different shapes and sizes (mean length, width, and height of the brains were 16.5, 14.3 and 12.1 cm for man, and 15.6, 13.5 and 11.4 cm for woman) from the template based on Caucasian (18.3, 14.2, and 13.3 cm). MRI and PET templates developed in this study will provide the framework for more accurate stereotactic standardization and anatomical localization.

Original language	English
Pages (from-to)	483-488
Number of pages	6
Journal	Journal of Korean medical science
Volume	20
Issue number	3
DOIs	https://doi.org/10.3346/jkms.2005.20.3.483
Publication status	Published - 2005 Jun

All Science Journal Classification (ASJC) codes

Medicine(all)

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10.3346/jkms.2005.20.3.483

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title = "Development of Korean standard brain templates",

abstract = "We developed age, gender and ethnic specific brain templates based on MR and Positron-Emission Tomography (PET) images of Korean normal volunteers. Seventy-eight normal right-handed volunteers (M/F=49/29) underwent 3D T1-weighted SPGR MR and F-18-FDG PET scans. For the generation of standard templates, an optimal target brain that has the average global hemispheric shape was selected for each gender. MR images were then spatially normalized by linear transformation to the target brains, and normalization parameters were reapplied to PET images. Subjects were subdivided into 2 groups for each gender: the young/midlife (<55 yr) and the elderly groups. Young and elderly MRI/PET templates were composed by averaging the spatially normalized images. Korean templates showed different shapes and sizes (mean length, width, and height of the brains were 16.5, 14.3 and 12.1 cm for man, and 15.6, 13.5 and 11.4 cm for woman) from the template based on Caucasian (18.3, 14.2, and 13.3 cm). MRI and PET templates developed in this study will provide the framework for more accurate stereotactic standardization and anatomical localization.",

author = "Jae, {Sung Lee} and Dong, {Soo Lee} and Jinsu Kim and Yu, {Kyeong Kim} and Eunjoo Kang and Hyejin Kang and Keon, {Wook Kang} and Jong, {Min Lee} and Kim, {Jae Jin} and Park, {Hae Jeong} and Jun, {Soo Kwon} and Sun, {I. Kim} and Tae, {Woo Yoo} and Chang, {Kee Hyun} and Myung, {Chul Lee}",

year = "2005",

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doi = "10.3346/jkms.2005.20.3.483",

language = "English",

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pages = "483--488",

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publisher = "Korean Academy of Medical Science",

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AU - Jae, Sung Lee

AU - Dong, Soo Lee

AU - Kim, Jinsu

AU - Yu, Kyeong Kim

AU - Kang, Eunjoo

AU - Kang, Hyejin

AU - Keon, Wook Kang

AU - Jong, Min Lee

AU - Kim, Jae Jin

AU - Park, Hae Jeong

AU - Jun, Soo Kwon

AU - Sun, I. Kim

AU - Tae, Woo Yoo

AU - Chang, Kee Hyun

AU - Myung, Chul Lee

PY - 2005/6

Y1 - 2005/6

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Development of Korean standard brain templates

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