TY - GEN
T1 - Development of multiplexed silicon dual microring sensor for the detection of bladder cancer markers
AU - Kim, Kyung Woo
AU - Song, Junfeng
AU - Liu, Qing
AU - Kee, Jack Sheng
AU - Shin, Yong
AU - Park, Mi Kyung
PY - 2012
Y1 - 2012
N2 - We propose an efficient multiplexed sensing system for detecting bladder cancer biomarkers without invasiveness, labeling, and high cost using a silicon-based dual microring resonator biosensor. The dual microring biosensor consists of a sensing microring and an electrical tracing microring. The working principle of the sensor is that a resonance wavelength shift of sensing ring is induced by the refractive index change resulted from biomarker binding to the ligand on the sensing microring. Then, the shift is traced and determined by the tracing ring through direct voltage supply. Also, we have shown the specific detection of HER-2 protein which is known as one of bladder cancer biomarker using the dual microring sensor.
AB - We propose an efficient multiplexed sensing system for detecting bladder cancer biomarkers without invasiveness, labeling, and high cost using a silicon-based dual microring resonator biosensor. The dual microring biosensor consists of a sensing microring and an electrical tracing microring. The working principle of the sensor is that a resonance wavelength shift of sensing ring is induced by the refractive index change resulted from biomarker binding to the ligand on the sensing microring. Then, the shift is traced and determined by the tracing ring through direct voltage supply. Also, we have shown the specific detection of HER-2 protein which is known as one of bladder cancer biomarker using the dual microring sensor.
UR - http://www.scopus.com/inward/record.url?scp=84874443708&partnerID=8YFLogxK
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U2 - 10.1109/PGC.2012.6458029
DO - 10.1109/PGC.2012.6458029
M3 - Conference contribution
AN - SCOPUS:84874443708
SN - 9781467325165
T3 - 2012 Photonics Global Conference, PGC 2012
BT - 2012 Photonics Global Conference, PGC 2012
T2 - 2012 Photonics Global Conference, PGC 2012
Y2 - 13 December 2012 through 16 December 2012
ER -