Developmental and reproductive consequences of prolonged non-aging dauer in Caenorhabditis elegans

Sunhee Kim; Young Ki Paik

doi:10.1016/j.bbrc.2008.01.131

Developmental and reproductive consequences of prolonged non-aging dauer in Caenorhabditis elegans

Sunhee Kim, Young Ki Paik

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

When Caenorhabditis elegans encounters harsh environmental conditions, it enters a non-aging diapause (dauer), an alternative larval stage capable of long-term survival. This replaces the stage of normal development critical for development of the reproductive organs. Here, we report that increased duration of diapause causes a delay in post-dauer development, and also causes severe defects in the reproductive development of males and hermaphrodites. Thus, the dauer state, while allowing for survival under adverse conditions, has important developmental and reproductive consequences. This effect is more pronounced in males, possibly accounting for the increased survival of C. elegans hermaphrodites in challenging environmental conditions.

Original language	English
Pages (from-to)	588-592
Number of pages	5
Journal	Biochemical and Biophysical Research Communications
Volume	368
Issue number	3
DOIs	https://doi.org/10.1016/j.bbrc.2008.01.131
Publication status	Published - 2008 Apr 11

Bibliographical note

Funding Information:
This work was supported by Forest Science & Technology Projects (No. S110707L0501501 to YKP) provided by Korea Forest Service, and a grant from the Basic Research Program through KOSEF (R01-2005-000-11021-0).

All Science Journal Classification (ASJC) codes

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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10.1016/j.bbrc.2008.01.131

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abstract = "When Caenorhabditis elegans encounters harsh environmental conditions, it enters a non-aging diapause (dauer), an alternative larval stage capable of long-term survival. This replaces the stage of normal development critical for development of the reproductive organs. Here, we report that increased duration of diapause causes a delay in post-dauer development, and also causes severe defects in the reproductive development of males and hermaphrodites. Thus, the dauer state, while allowing for survival under adverse conditions, has important developmental and reproductive consequences. This effect is more pronounced in males, possibly accounting for the increased survival of C. elegans hermaphrodites in challenging environmental conditions.",

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Developmental and reproductive consequences of prolonged non-aging dauer in Caenorhabditis elegans

Abstract

Bibliographical note

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