Diagnosis, Management, and Treatment of Vernal Keratoconjunctivitis in Asia: Recommendations From the Management of Vernal Keratoconjunctivitis in Asia Expert Working Group

Jodhbir S. Mehta, Wei Li Chen, Arthur C.K. Cheng, Le Xuan Cung, Ivo J. Dualan, Ramesh Kekunnaya, Nurliza Khaliddin, Tae Im Kim, Douglas K. Lam, Seo Wei Leo, Florence Manurung, Nattaporn Tesavibul, Dominique Bremond-Gignac

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1 Citation (Scopus)

Abstract

Vernal keratoconjunctivitis (VKC) is an underdiagnosed and underrecognized ocular surface disease with limited epidemiological data in Asia. It is more prevalent in warm, dry, and windy climates, and often has a substantial impact on a patient’s quality of life. In rare cases, VKC can be associated with vision loss, either through corticosteroid overuse or inadequate treatment of persistent inflammation. As a potentially severe and complex disease, there is variability with how VKC is managed across Asia and among the various allergic eye diseases. Diagnosis and treatment of patients with VKC is a challenge for many ophthalmologists, since no precise diagnostic criteria have been established, the pathogenesis of the disease is unclear, and anti-allergic treatments are often ineffective in patients with moderate or severe disease. In addition, the choice of treatment and management strategies used for patients varies greatly from country to country and physician to physician. This may be because of a lack of well-defined, standardized guidelines. In response, the Management of Vernal Keratoconjunctivitis in Asia (MOVIA) Expert Working Group (13 experts) completed a consensus program to evaluate, review, and develop best-practice recommendations for the assessment, diagnosis, and management of VKC in Asia. The expert-led recommendations are summarized in this article and based on the currently available evidence alongside the clinical expertise of ophthalmologists from across Asia with specialism and interest in the ocular surface, VKC, and pediatric ophthalmology.

Original languageEnglish
Article number882240
JournalFrontiers in Medicine
Volume9
DOIs
Publication statusPublished - 2022 Aug 1

Bibliographical note

Funding Information:
We are members of the MOVIA Expert Working Group. The MOVIA Advisory Board meeting was organized and funded by Santen Pharmaceutical Asia Pte. Ltd. Santen Asia had negligible input into the content of this article outside of forming the expert group. Medical writing and logistical support were provided by Synergy Vision. The funders (Santen Asia) had no role in the interpretation and development of the recommendations or in the writing of the manuscript.

Funding Information:
JSM was a consultant for, or has received research grants or travel grants from, Carl Zeiss, Cordlife, Leica, Millipore Sigma, Moria, Network Medical, Santen, Trefoil, and Ziemer. DBG was a consultant for Alcon/Novartis, Cooper, Hoya Surgical Optics, Santen, and Théa, and has received research grants or travel grants from Hoya Surgical Optics, Santen, and Théa. ACKC has received travel grants from Santen. TIK was a medical advisory board member for Hoya Surgical Optics and Santen. DKL has received travel grants from Johnson & Johnson Vision and Santen. SWL has received travel grants from Allergan, Carl Zeiss, and Santen. SWL was employed by Dr Leo Adult & Paediatric Eye Specialist Pte Ltd. NT was a medical advisory board member and educational speaker for Santen and has received travel grants from Santen and TRB Chemidica. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Funding Information:
We are members of the MOVIA Expert Working Group. The MOVIA Advisory Board meeting was organized and funded by Santen Pharmaceutical Asia Pte. Ltd. Santen Asia had negligible input into the content of this article outside of forming the expert group. Medical writing and logistical support were provided by Synergy Vision. The funders (Santen Asia) had no role in the interpretation and development of the recommendations or in the writing of the manuscript.

Publisher Copyright:
Copyright © 2022 Mehta, Chen, Cheng, Cung, Dualan, Kekunnaya, Khaliddin, Kim, Lam, Leo, Manurung, Tesavibul and Bremond-Gignac.

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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