Diagnosis of hepatitis B

Jeong Eun Song, doyoung kim

Research output: Contribution to journalReview article

16 Citations (Scopus)

Abstract

Hepatitis B virus (HBV) infection is a major global health problems leading to severe liver disease such as cirrhosis and hepatocellular carcinoma (HCC). HBV is a circular, partly double-stranded DNA virus with various serological markers: hepatitis B surface antigen (HBsAg) and anti-HBs, anti-HBc IgM and IgG, and hepatitis B e antigen (HBeAg) and anti-HBe. It is transmitted by sexual, parenteral and vertical route. One significant method to diminish the burden of this disease is timely diagnosis of acute, chronic and occult cases of HBV. First step of HBV diagnosis is achieved by using serological markers for detecting antigens and antibodies. In order to verify first step of diagnosis, to quantify viral load and to identify genotypes, quantitative or qualitative molecular tests are used. In this article, the serological and molecular tests for diagnosis of HBV infection will be reviewed.

Original languageEnglish
Article number338
JournalAnnals of Translational Medicine
Volume4
Issue number18
DOIs
Publication statusPublished - 2016 Sep 1

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Hepatitis B
Hepatitis B virus
Virus Diseases
DNA Viruses
Hepatitis B e Antigens
Differentiation Antigens
Serologic Tests
Hepatitis B Surface Antigens
Viral Load
Liver Diseases
Hepatocellular Carcinoma
Fibrosis
Genotype
Antibodies
DNA

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Song, Jeong Eun ; kim, doyoung. / Diagnosis of hepatitis B. In: Annals of Translational Medicine. 2016 ; Vol. 4, No. 18.
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Diagnosis of hepatitis B. / Song, Jeong Eun; kim, doyoung.

In: Annals of Translational Medicine, Vol. 4, No. 18, 338, 01.09.2016.

Research output: Contribution to journalReview article

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AU - Song, Jeong Eun

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