[Diagnosis of irritable bowel syndrome: a systematic review].

Jung Ho Park, Jeong Sik Byeon, Woon Geon Shin, Young Hun Yoon, Jae Hee Cheon, Kwang Jae Lee, Jyojin Park, Society of Neurogastroenterology Korean Society of Neurogastroenterology

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Irritable bowel syndrome(IBS) is a very common functional gastrointestinal disorder characterized by abdominal discomfort, bloating, and disturbed defecation. Patients with IBS have a tendency to visit physicians more frequently than those without IBS, thus annual economic consequences of IBS in the Western countries are substantial. Therefore, guidelines for the diagnosis and treatment of IBS patients have been designed to give a favored effect on the Department of Gastroenterology's overall performance. A variety of criteria have been developed to identify a combination of symptoms to diagnose IBS, including Manning and Rome I, II, and III criteria. Overall, Manning's criteria had a pooled sensitivity and specificity, 78% and 72%, respectively. In addition, the Rome I criteria had a sensitivity and specificity, 71% and 85%, respectively. However, none described the accuracy of Rome II and III yet. Alarm features such as rectal bleeding and nocturnal pain offer little discriminative value in separating patients with IBS from those with organic diseases. Even though anemia and weight loss have poor sensitivity for organic diseases, they offer very good specificity. Since specific biomarker of IBS is not yet available, diagnostic tests are frequently performed to exclude organic diseases. However, the accuracy of diagnostic tests is disappointing. CBC, chemistry, thyroid function test, stool exam, ultrasonography, hydrogen breath test, erythrocyte sedimentation rate, and C-reactive protein have all very limited accuracy in discriminating IBS from organic diseases. This systemic review is targeted to establish the strategy of IBS treatment, which is very necessary for the current clinical practice.

Original languageEnglish
Pages (from-to)308-315
Number of pages8
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume55
Issue number5
DOIs
Publication statusPublished - 2010 May

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Irritable Bowel Syndrome
Routine Diagnostic Tests
Thyroid Function Tests
Sensitivity and Specificity
Breath Tests
Defecation
Gastrointestinal Diseases
Blood Sedimentation
Gastroenterology
C-Reactive Protein
Anemia
Weight Loss
Hydrogen
Ultrasonography
Biomarkers
Economics
Guidelines
Hemorrhage
Physicians
Pain

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Park, J. H., Byeon, J. S., Shin, W. G., Yoon, Y. H., Cheon, J. H., Lee, K. J., ... Korean Society of Neurogastroenterology, S. O. N. (2010). [Diagnosis of irritable bowel syndrome: a systematic review]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 55(5), 308-315. https://doi.org/10.4166/kjg.2010.55.5.308
Park, Jung Ho ; Byeon, Jeong Sik ; Shin, Woon Geon ; Yoon, Young Hun ; Cheon, Jae Hee ; Lee, Kwang Jae ; Park, Jyojin ; Korean Society of Neurogastroenterology, Society of Neurogastroenterology. / [Diagnosis of irritable bowel syndrome : a systematic review]. In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi. 2010 ; Vol. 55, No. 5. pp. 308-315.
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Park, JH, Byeon, JS, Shin, WG, Yoon, YH, Cheon, JH, Lee, KJ, Park, J & Korean Society of Neurogastroenterology, SON 2010, '[Diagnosis of irritable bowel syndrome: a systematic review].', The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, vol. 55, no. 5, pp. 308-315. https://doi.org/10.4166/kjg.2010.55.5.308

[Diagnosis of irritable bowel syndrome : a systematic review]. / Park, Jung Ho; Byeon, Jeong Sik; Shin, Woon Geon; Yoon, Young Hun; Cheon, Jae Hee; Lee, Kwang Jae; Park, Jyojin; Korean Society of Neurogastroenterology, Society of Neurogastroenterology.

In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, Vol. 55, No. 5, 05.2010, p. 308-315.

Research output: Contribution to journalReview article

TY - JOUR

T1 - [Diagnosis of irritable bowel syndrome

T2 - a systematic review].

AU - Park, Jung Ho

AU - Byeon, Jeong Sik

AU - Shin, Woon Geon

AU - Yoon, Young Hun

AU - Cheon, Jae Hee

AU - Lee, Kwang Jae

AU - Park, Jyojin

AU - Korean Society of Neurogastroenterology, Society of Neurogastroenterology

PY - 2010/5

Y1 - 2010/5

N2 - Irritable bowel syndrome(IBS) is a very common functional gastrointestinal disorder characterized by abdominal discomfort, bloating, and disturbed defecation. Patients with IBS have a tendency to visit physicians more frequently than those without IBS, thus annual economic consequences of IBS in the Western countries are substantial. Therefore, guidelines for the diagnosis and treatment of IBS patients have been designed to give a favored effect on the Department of Gastroenterology's overall performance. A variety of criteria have been developed to identify a combination of symptoms to diagnose IBS, including Manning and Rome I, II, and III criteria. Overall, Manning's criteria had a pooled sensitivity and specificity, 78% and 72%, respectively. In addition, the Rome I criteria had a sensitivity and specificity, 71% and 85%, respectively. However, none described the accuracy of Rome II and III yet. Alarm features such as rectal bleeding and nocturnal pain offer little discriminative value in separating patients with IBS from those with organic diseases. Even though anemia and weight loss have poor sensitivity for organic diseases, they offer very good specificity. Since specific biomarker of IBS is not yet available, diagnostic tests are frequently performed to exclude organic diseases. However, the accuracy of diagnostic tests is disappointing. CBC, chemistry, thyroid function test, stool exam, ultrasonography, hydrogen breath test, erythrocyte sedimentation rate, and C-reactive protein have all very limited accuracy in discriminating IBS from organic diseases. This systemic review is targeted to establish the strategy of IBS treatment, which is very necessary for the current clinical practice.

AB - Irritable bowel syndrome(IBS) is a very common functional gastrointestinal disorder characterized by abdominal discomfort, bloating, and disturbed defecation. Patients with IBS have a tendency to visit physicians more frequently than those without IBS, thus annual economic consequences of IBS in the Western countries are substantial. Therefore, guidelines for the diagnosis and treatment of IBS patients have been designed to give a favored effect on the Department of Gastroenterology's overall performance. A variety of criteria have been developed to identify a combination of symptoms to diagnose IBS, including Manning and Rome I, II, and III criteria. Overall, Manning's criteria had a pooled sensitivity and specificity, 78% and 72%, respectively. In addition, the Rome I criteria had a sensitivity and specificity, 71% and 85%, respectively. However, none described the accuracy of Rome II and III yet. Alarm features such as rectal bleeding and nocturnal pain offer little discriminative value in separating patients with IBS from those with organic diseases. Even though anemia and weight loss have poor sensitivity for organic diseases, they offer very good specificity. Since specific biomarker of IBS is not yet available, diagnostic tests are frequently performed to exclude organic diseases. However, the accuracy of diagnostic tests is disappointing. CBC, chemistry, thyroid function test, stool exam, ultrasonography, hydrogen breath test, erythrocyte sedimentation rate, and C-reactive protein have all very limited accuracy in discriminating IBS from organic diseases. This systemic review is targeted to establish the strategy of IBS treatment, which is very necessary for the current clinical practice.

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