Diagnosis of viable myocardium using velocity data of doppler myocardial imaging

Comparison with positron emission tomography

Hyun Suk Yang, Soo Jin Kang, Jae Kwan Song, Dae Hyuk Moon, Jong Min Song, Duk Hyun Kang, Cheol Whan Lee, Myeongki Hong, Jae Joong Kim, Seong Wook Park, Seung Jung Park

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

To test whether velocity data of Doppler myocardial imaging (DMI) at rest is useful for diagnosis of myocardial viability, 25 consecutive patients (age 64 ± 10 years) with regional wall-motion abnormalities at the left anterior descending coronary artery territory and left ventricular dysfunction (ejection fraction: 31 ± 7%) underwent both DMI at rest and positron emission tomography. The peak systolic velocity (Vpeak) and postsystolic thickening (PST) velocity were measured in myocardial segments of left anterior descending coronary artery territory from apical views. A total of 71 segments were classified by positron emission tomography as normal or viable in 38 (group A) and nonviable in 33 (group B). Although Vpeak did not show any difference between groups (1.81 ± 1.77 vs 1.29 ± 0.94 cm/s, P = .107), PST velocity was significantly higher in group A (2.48 ± 1.68 vs 0.89 ± 0.72 cm/s, P < .001). The sensitivity and specificity of PST velocity > 2.0 cm/s for diagnosis of viability were 61% (23/38) and 97% (32/33), respectively. In segments with PST velocity was ≤2.0 cm/s, V peak > 1.8 cm/s could discriminate group A from B with a sensitivity of 67% (10/15) and a specificity of 91% (29/32). The algorithm using both PST velocity and Vpeak of DMI showed sensitivity and specificity of 87% and 88%, respectively, for diagnosis of myocardial viability. Velocity data of DMI at rest provides robust information regarding viability in selected patients, and an advantage of this technique is that no stress testing is needed.

Original languageEnglish
Pages (from-to)933-940
Number of pages8
JournalJournal of the American Society of Echocardiography
Volume17
Issue number9
DOIs
Publication statusPublished - 2004 Sep 1

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Positron-Emission Tomography
Myocardium
Coronary Vessels
Left Ventricular Dysfunction
Stroke Volume
Sensitivity and Specificity

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Yang, Hyun Suk ; Kang, Soo Jin ; Song, Jae Kwan ; Moon, Dae Hyuk ; Song, Jong Min ; Kang, Duk Hyun ; Lee, Cheol Whan ; Hong, Myeongki ; Kim, Jae Joong ; Park, Seong Wook ; Park, Seung Jung. / Diagnosis of viable myocardium using velocity data of doppler myocardial imaging : Comparison with positron emission tomography. In: Journal of the American Society of Echocardiography. 2004 ; Vol. 17, No. 9. pp. 933-940.
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abstract = "To test whether velocity data of Doppler myocardial imaging (DMI) at rest is useful for diagnosis of myocardial viability, 25 consecutive patients (age 64 ± 10 years) with regional wall-motion abnormalities at the left anterior descending coronary artery territory and left ventricular dysfunction (ejection fraction: 31 ± 7{\%}) underwent both DMI at rest and positron emission tomography. The peak systolic velocity (Vpeak) and postsystolic thickening (PST) velocity were measured in myocardial segments of left anterior descending coronary artery territory from apical views. A total of 71 segments were classified by positron emission tomography as normal or viable in 38 (group A) and nonviable in 33 (group B). Although Vpeak did not show any difference between groups (1.81 ± 1.77 vs 1.29 ± 0.94 cm/s, P = .107), PST velocity was significantly higher in group A (2.48 ± 1.68 vs 0.89 ± 0.72 cm/s, P < .001). The sensitivity and specificity of PST velocity > 2.0 cm/s for diagnosis of viability were 61{\%} (23/38) and 97{\%} (32/33), respectively. In segments with PST velocity was ≤2.0 cm/s, V peak > 1.8 cm/s could discriminate group A from B with a sensitivity of 67{\%} (10/15) and a specificity of 91{\%} (29/32). The algorithm using both PST velocity and Vpeak of DMI showed sensitivity and specificity of 87{\%} and 88{\%}, respectively, for diagnosis of myocardial viability. Velocity data of DMI at rest provides robust information regarding viability in selected patients, and an advantage of this technique is that no stress testing is needed.",
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Diagnosis of viable myocardium using velocity data of doppler myocardial imaging : Comparison with positron emission tomography. / Yang, Hyun Suk; Kang, Soo Jin; Song, Jae Kwan; Moon, Dae Hyuk; Song, Jong Min; Kang, Duk Hyun; Lee, Cheol Whan; Hong, Myeongki; Kim, Jae Joong; Park, Seong Wook; Park, Seung Jung.

In: Journal of the American Society of Echocardiography, Vol. 17, No. 9, 01.09.2004, p. 933-940.

Research output: Contribution to journalArticle

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T1 - Diagnosis of viable myocardium using velocity data of doppler myocardial imaging

T2 - Comparison with positron emission tomography

AU - Yang, Hyun Suk

AU - Kang, Soo Jin

AU - Song, Jae Kwan

AU - Moon, Dae Hyuk

AU - Song, Jong Min

AU - Kang, Duk Hyun

AU - Lee, Cheol Whan

AU - Hong, Myeongki

AU - Kim, Jae Joong

AU - Park, Seong Wook

AU - Park, Seung Jung

PY - 2004/9/1

Y1 - 2004/9/1

N2 - To test whether velocity data of Doppler myocardial imaging (DMI) at rest is useful for diagnosis of myocardial viability, 25 consecutive patients (age 64 ± 10 years) with regional wall-motion abnormalities at the left anterior descending coronary artery territory and left ventricular dysfunction (ejection fraction: 31 ± 7%) underwent both DMI at rest and positron emission tomography. The peak systolic velocity (Vpeak) and postsystolic thickening (PST) velocity were measured in myocardial segments of left anterior descending coronary artery territory from apical views. A total of 71 segments were classified by positron emission tomography as normal or viable in 38 (group A) and nonviable in 33 (group B). Although Vpeak did not show any difference between groups (1.81 ± 1.77 vs 1.29 ± 0.94 cm/s, P = .107), PST velocity was significantly higher in group A (2.48 ± 1.68 vs 0.89 ± 0.72 cm/s, P < .001). The sensitivity and specificity of PST velocity > 2.0 cm/s for diagnosis of viability were 61% (23/38) and 97% (32/33), respectively. In segments with PST velocity was ≤2.0 cm/s, V peak > 1.8 cm/s could discriminate group A from B with a sensitivity of 67% (10/15) and a specificity of 91% (29/32). The algorithm using both PST velocity and Vpeak of DMI showed sensitivity and specificity of 87% and 88%, respectively, for diagnosis of myocardial viability. Velocity data of DMI at rest provides robust information regarding viability in selected patients, and an advantage of this technique is that no stress testing is needed.

AB - To test whether velocity data of Doppler myocardial imaging (DMI) at rest is useful for diagnosis of myocardial viability, 25 consecutive patients (age 64 ± 10 years) with regional wall-motion abnormalities at the left anterior descending coronary artery territory and left ventricular dysfunction (ejection fraction: 31 ± 7%) underwent both DMI at rest and positron emission tomography. The peak systolic velocity (Vpeak) and postsystolic thickening (PST) velocity were measured in myocardial segments of left anterior descending coronary artery territory from apical views. A total of 71 segments were classified by positron emission tomography as normal or viable in 38 (group A) and nonviable in 33 (group B). Although Vpeak did not show any difference between groups (1.81 ± 1.77 vs 1.29 ± 0.94 cm/s, P = .107), PST velocity was significantly higher in group A (2.48 ± 1.68 vs 0.89 ± 0.72 cm/s, P < .001). The sensitivity and specificity of PST velocity > 2.0 cm/s for diagnosis of viability were 61% (23/38) and 97% (32/33), respectively. In segments with PST velocity was ≤2.0 cm/s, V peak > 1.8 cm/s could discriminate group A from B with a sensitivity of 67% (10/15) and a specificity of 91% (29/32). The algorithm using both PST velocity and Vpeak of DMI showed sensitivity and specificity of 87% and 88%, respectively, for diagnosis of myocardial viability. Velocity data of DMI at rest provides robust information regarding viability in selected patients, and an advantage of this technique is that no stress testing is needed.

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