Diagnostic Yield and Clinical Impact of Video Capsule Endoscopy in Patients with Chronic Diarrhea: A Korean Multicenter CAPENTRY Study

Korean Gut Image Study Group

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background/Aims: In some cases, chronic diarrhea is unexplained, and small bowel disorders may be one of the causes. The aim of this study was to assess the diagnostic yield and clinical impact of video capsule endoscopy (VCE) in patients with chronic diarrhea.

Methods: We retrospectively analyzed records from October 2002 to August 2013 in the VCE nationwide database registry (n=2,964). Ninety-one patients from 15 medical centers (60 males and 31 females; mean age, 47±19 years) were evaluated for VCE as a result of chronic diarrhea.

Results: The duration of chronic diarrhea was 8.3±14.7 months. The positive diagnostic yield of VCE was 42.9% (39/91). However, 15.4% (14/91) exhibited an inconsistent result, and 41.8% (38/91) were negative. Abnormal findings consistent with chronic diarrhea included erosions/aphthous ulcers (19.8%), ulcers (17.6%), mucosal erythema (3.3%), edema (1.1%), and luminal narrowing (1.1%). The most common diagnoses were functional diarrhea associated with irritable bowel syndrome in 37 patients (40.7%) and Crohn's disease in 18 patients (19.8%). After VCE examination, the diagnosis was changed in 34.1% of the patients (31/91). Hematochezia (odds ratio [OR], 8.802; 95% confidence interval [CI], 2.126 to 36.441) and hypoalbuminemia (OR, 4.811; 95% CI, 1.241 to 18.655) are predictive factors of a positive diagnostic yield.

Conclusions: VCE had a favorable diagnostic yield and clinical impact on the management of patients with chronic diarrhea.

Original languageEnglish
Pages (from-to)253-260
Number of pages8
JournalGut and liver
Volume11
Issue number2
DOIs
Publication statusPublished - 2017 Mar 15

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Capsule Endoscopy
Multicenter Studies
Diarrhea
Odds Ratio
Confidence Intervals
Aphthous Stomatitis
Hypoalbuminemia
Gastrointestinal Hemorrhage
Irritable Bowel Syndrome
Erythema
Crohn Disease
Ulcer
Registries
Edema
Databases

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

@article{5ff81184e67f47fdb2b4909d9fd67af2,
title = "Diagnostic Yield and Clinical Impact of Video Capsule Endoscopy in Patients with Chronic Diarrhea: A Korean Multicenter CAPENTRY Study",
abstract = "Background/Aims: In some cases, chronic diarrhea is unexplained, and small bowel disorders may be one of the causes. The aim of this study was to assess the diagnostic yield and clinical impact of video capsule endoscopy (VCE) in patients with chronic diarrhea.Methods: We retrospectively analyzed records from October 2002 to August 2013 in the VCE nationwide database registry (n=2,964). Ninety-one patients from 15 medical centers (60 males and 31 females; mean age, 47±19 years) were evaluated for VCE as a result of chronic diarrhea.Results: The duration of chronic diarrhea was 8.3±14.7 months. The positive diagnostic yield of VCE was 42.9{\%} (39/91). However, 15.4{\%} (14/91) exhibited an inconsistent result, and 41.8{\%} (38/91) were negative. Abnormal findings consistent with chronic diarrhea included erosions/aphthous ulcers (19.8{\%}), ulcers (17.6{\%}), mucosal erythema (3.3{\%}), edema (1.1{\%}), and luminal narrowing (1.1{\%}). The most common diagnoses were functional diarrhea associated with irritable bowel syndrome in 37 patients (40.7{\%}) and Crohn's disease in 18 patients (19.8{\%}). After VCE examination, the diagnosis was changed in 34.1{\%} of the patients (31/91). Hematochezia (odds ratio [OR], 8.802; 95{\%} confidence interval [CI], 2.126 to 36.441) and hypoalbuminemia (OR, 4.811; 95{\%} CI, 1.241 to 18.655) are predictive factors of a positive diagnostic yield.Conclusions: VCE had a favorable diagnostic yield and clinical impact on the management of patients with chronic diarrhea.",
author = "{Korean Gut Image Study Group} and Song, {Hyun Joo} and Moon, {Jeong Seop} and Jeon, {Seong Ran} and Kim, {Jin Oh} and Jinsu Kim and Cheung, {Dae Young} and Choi, {Myung Gyu} and Lim, {Yun Jeong} and Shim, {Ki Nam} and Ye, {Byong Duk} and Cheon, {Jae Hee} and Park, {Cheol Hee} and Kim, {Hyun Soo} and Kim, {Ji Hyun} and Chang, {Dong Kyung} and Do, {Jae Hyuk} and Kim, {Kyeong Ok} and Jang, {Byung Ik} and Shin, {Sung Jae}",
year = "2017",
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language = "English",
volume = "11",
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}

Diagnostic Yield and Clinical Impact of Video Capsule Endoscopy in Patients with Chronic Diarrhea : A Korean Multicenter CAPENTRY Study. / Korean Gut Image Study Group.

In: Gut and liver, Vol. 11, No. 2, 15.03.2017, p. 253-260.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Diagnostic Yield and Clinical Impact of Video Capsule Endoscopy in Patients with Chronic Diarrhea

T2 - A Korean Multicenter CAPENTRY Study

AU - Korean Gut Image Study Group

AU - Song, Hyun Joo

AU - Moon, Jeong Seop

AU - Jeon, Seong Ran

AU - Kim, Jin Oh

AU - Kim, Jinsu

AU - Cheung, Dae Young

AU - Choi, Myung Gyu

AU - Lim, Yun Jeong

AU - Shim, Ki Nam

AU - Ye, Byong Duk

AU - Cheon, Jae Hee

AU - Park, Cheol Hee

AU - Kim, Hyun Soo

AU - Kim, Ji Hyun

AU - Chang, Dong Kyung

AU - Do, Jae Hyuk

AU - Kim, Kyeong Ok

AU - Jang, Byung Ik

AU - Shin, Sung Jae

PY - 2017/3/15

Y1 - 2017/3/15

N2 - Background/Aims: In some cases, chronic diarrhea is unexplained, and small bowel disorders may be one of the causes. The aim of this study was to assess the diagnostic yield and clinical impact of video capsule endoscopy (VCE) in patients with chronic diarrhea.Methods: We retrospectively analyzed records from October 2002 to August 2013 in the VCE nationwide database registry (n=2,964). Ninety-one patients from 15 medical centers (60 males and 31 females; mean age, 47±19 years) were evaluated for VCE as a result of chronic diarrhea.Results: The duration of chronic diarrhea was 8.3±14.7 months. The positive diagnostic yield of VCE was 42.9% (39/91). However, 15.4% (14/91) exhibited an inconsistent result, and 41.8% (38/91) were negative. Abnormal findings consistent with chronic diarrhea included erosions/aphthous ulcers (19.8%), ulcers (17.6%), mucosal erythema (3.3%), edema (1.1%), and luminal narrowing (1.1%). The most common diagnoses were functional diarrhea associated with irritable bowel syndrome in 37 patients (40.7%) and Crohn's disease in 18 patients (19.8%). After VCE examination, the diagnosis was changed in 34.1% of the patients (31/91). Hematochezia (odds ratio [OR], 8.802; 95% confidence interval [CI], 2.126 to 36.441) and hypoalbuminemia (OR, 4.811; 95% CI, 1.241 to 18.655) are predictive factors of a positive diagnostic yield.Conclusions: VCE had a favorable diagnostic yield and clinical impact on the management of patients with chronic diarrhea.

AB - Background/Aims: In some cases, chronic diarrhea is unexplained, and small bowel disorders may be one of the causes. The aim of this study was to assess the diagnostic yield and clinical impact of video capsule endoscopy (VCE) in patients with chronic diarrhea.Methods: We retrospectively analyzed records from October 2002 to August 2013 in the VCE nationwide database registry (n=2,964). Ninety-one patients from 15 medical centers (60 males and 31 females; mean age, 47±19 years) were evaluated for VCE as a result of chronic diarrhea.Results: The duration of chronic diarrhea was 8.3±14.7 months. The positive diagnostic yield of VCE was 42.9% (39/91). However, 15.4% (14/91) exhibited an inconsistent result, and 41.8% (38/91) were negative. Abnormal findings consistent with chronic diarrhea included erosions/aphthous ulcers (19.8%), ulcers (17.6%), mucosal erythema (3.3%), edema (1.1%), and luminal narrowing (1.1%). The most common diagnoses were functional diarrhea associated with irritable bowel syndrome in 37 patients (40.7%) and Crohn's disease in 18 patients (19.8%). After VCE examination, the diagnosis was changed in 34.1% of the patients (31/91). Hematochezia (odds ratio [OR], 8.802; 95% confidence interval [CI], 2.126 to 36.441) and hypoalbuminemia (OR, 4.811; 95% CI, 1.241 to 18.655) are predictive factors of a positive diagnostic yield.Conclusions: VCE had a favorable diagnostic yield and clinical impact on the management of patients with chronic diarrhea.

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