Dielectric imaging for differentiation between cancer and inflammation in vivo

Rimi Lee, Sun Mi Lee, Hyung Joon Kim, Sook Young Kim, Mina Son, Jun Ho Song, Khulan Lkhamsuren, In Ho Park, In Hong Choi, Young Nyun Park, Jeon Soo Shin, Kyung Hwa Yoo

Research output: Contribution to journalArticle

Abstract

In this study, we develop an in vivo dielectric imaging technique that measures capacitance using pin-type electrode arrays. Compared to normal tissues, cancer tissues exhibit higher capacitance values, allowing us to image the cancer region and monitor the chemotherapeutic effects of cancer in real-time. A comparison with the histopathological results shows that the in vivo dielectric imaging technique is able to detect small tumors (<3 mm) and tumor-associated changes. In addition, we demonstrate that cancer and inflammation may be distinguished by measuring the capacitance images at different frequencies. In contrast, the positron emission tomography using 2-[18F]-fluoro-2-deoxy-D-glucose was not capable of discriminating between cancer and inflammation.

Original languageEnglish
Article number13137
JournalScientific reports
Volume7
Issue number1
DOIs
Publication statusPublished - 2017 Dec 1

All Science Journal Classification (ASJC) codes

  • General

Fingerprint Dive into the research topics of 'Dielectric imaging for differentiation between cancer and inflammation in vivo'. Together they form a unique fingerprint.

  • Cite this

    Lee, R., Lee, S. M., Kim, H. J., Kim, S. Y., Son, M., Song, J. H., Lkhamsuren, K., Park, I. H., Choi, I. H., Park, Y. N., Shin, J. S., & Yoo, K. H. (2017). Dielectric imaging for differentiation between cancer and inflammation in vivo. Scientific reports, 7(1), [13137]. https://doi.org/10.1038/s41598-017-13545-3