Differential effects of green tea polyphenol on cellular responses in normal cells vs. cancer cells and its possible mechanisms

D. W. Han, B. J. Park, I. S. Lee, K. Y. Lee, J. K. Kim, S. H. Hyon, Jongchul Park

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The differential biological responsiveness to green tea polyphenols (GTP) and inclusion of NF-kB as a mechanism in normal cells, immortalized cell line and cancer cells, was investigated. Cell growth, alkaline phosphatase (ALP) activity, DNA cell cycle and morphology were also analyzed. It was observed that at the higher dose of GTP, number of cells decreased. It was found that GTP imparted differential dose-based growth and function inhibitory responses toward the carcinoma cells as compared to the normal cells.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
Publication statusPublished - 2004 Dec 1
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 2004 May 172004 May 21

Publication series

NameTransactions - 7th World Biomaterials Congress

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period04/5/1704/5/21

Fingerprint

Cells
Phosphatases
Cell growth
DNA
Tea
Polyphenols

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Han, D. W., Park, B. J., Lee, I. S., Lee, K. Y., Kim, J. K., Hyon, S. H., & Park, J. (2004). Differential effects of green tea polyphenol on cellular responses in normal cells vs. cancer cells and its possible mechanisms. In Transactions - 7th World Biomaterials Congress (Transactions - 7th World Biomaterials Congress).
Han, D. W. ; Park, B. J. ; Lee, I. S. ; Lee, K. Y. ; Kim, J. K. ; Hyon, S. H. ; Park, Jongchul. / Differential effects of green tea polyphenol on cellular responses in normal cells vs. cancer cells and its possible mechanisms. Transactions - 7th World Biomaterials Congress. 2004. (Transactions - 7th World Biomaterials Congress).
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abstract = "The differential biological responsiveness to green tea polyphenols (GTP) and inclusion of NF-kB as a mechanism in normal cells, immortalized cell line and cancer cells, was investigated. Cell growth, alkaline phosphatase (ALP) activity, DNA cell cycle and morphology were also analyzed. It was observed that at the higher dose of GTP, number of cells decreased. It was found that GTP imparted differential dose-based growth and function inhibitory responses toward the carcinoma cells as compared to the normal cells.",
author = "Han, {D. W.} and Park, {B. J.} and Lee, {I. S.} and Lee, {K. Y.} and Kim, {J. K.} and Hyon, {S. H.} and Jongchul Park",
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Han, DW, Park, BJ, Lee, IS, Lee, KY, Kim, JK, Hyon, SH & Park, J 2004, Differential effects of green tea polyphenol on cellular responses in normal cells vs. cancer cells and its possible mechanisms. in Transactions - 7th World Biomaterials Congress. Transactions - 7th World Biomaterials Congress, Transactions - 7th World Biomaterials Congress, Sydney, Australia, 04/5/17.

Differential effects of green tea polyphenol on cellular responses in normal cells vs. cancer cells and its possible mechanisms. / Han, D. W.; Park, B. J.; Lee, I. S.; Lee, K. Y.; Kim, J. K.; Hyon, S. H.; Park, Jongchul.

Transactions - 7th World Biomaterials Congress. 2004. (Transactions - 7th World Biomaterials Congress).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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AB - The differential biological responsiveness to green tea polyphenols (GTP) and inclusion of NF-kB as a mechanism in normal cells, immortalized cell line and cancer cells, was investigated. Cell growth, alkaline phosphatase (ALP) activity, DNA cell cycle and morphology were also analyzed. It was observed that at the higher dose of GTP, number of cells decreased. It was found that GTP imparted differential dose-based growth and function inhibitory responses toward the carcinoma cells as compared to the normal cells.

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Han DW, Park BJ, Lee IS, Lee KY, Kim JK, Hyon SH et al. Differential effects of green tea polyphenol on cellular responses in normal cells vs. cancer cells and its possible mechanisms. In Transactions - 7th World Biomaterials Congress. 2004. (Transactions - 7th World Biomaterials Congress).