Differential effects of green tea polyphenol on cellular responses in normal cells vs. cancer cells and its possible mechanisms

D. W. Han; B. J. Park; I. S. Lee; K. Y. Lee; J. K. Kim; S. H. Hyon; J. C. Park

Differential effects of green tea polyphenol on cellular responses in normal cells vs. cancer cells and its possible mechanisms

D. W. Han, B. J. Park, I. S. Lee, K. Y. Lee, J. K. Kim, S. H. Hyon, J. C. Park

Department of Medical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The differential biological responsiveness to green tea polyphenols (GTP) and inclusion of NF-kB as a mechanism in normal cells, immortalized cell line and cancer cells, was investigated. Cell growth, alkaline phosphatase (ALP) activity, DNA cell cycle and morphology were also analyzed. It was observed that at the higher dose of GTP, number of cells decreased. It was found that GTP imparted differential dose-based growth and function inhibitory responses toward the carcinoma cells as compared to the normal cells.

Original language	English
Title of host publication	Transactions - 7th World Biomaterials Congress
Pages	1203
Number of pages	1
Publication status	Published - 2004
Event	Transactions - 7th World Biomaterials Congress - Sydney, Australia Duration: 2004 May 17 → 2004 May 21

Publication series

Name	Transactions - 7th World Biomaterials Congress

Other

Other	Transactions - 7th World Biomaterials Congress
Country	Australia
City	Sydney
Period	04/5/17 → 04/5/21

All Science Journal Classification (ASJC) codes

Engineering(all)

Fingerprint Dive into the research topics of 'Differential effects of green tea polyphenol on cellular responses in normal cells vs. cancer cells and its possible mechanisms'. Together they form a unique fingerprint.

Cite this

@inproceedings{a20f0ed4e75644ae909dd574d7a629cc,

title = "Differential effects of green tea polyphenol on cellular responses in normal cells vs. cancer cells and its possible mechanisms",

abstract = "The differential biological responsiveness to green tea polyphenols (GTP) and inclusion of NF-kB as a mechanism in normal cells, immortalized cell line and cancer cells, was investigated. Cell growth, alkaline phosphatase (ALP) activity, DNA cell cycle and morphology were also analyzed. It was observed that at the higher dose of GTP, number of cells decreased. It was found that GTP imparted differential dose-based growth and function inhibitory responses toward the carcinoma cells as compared to the normal cells.",

author = "Han, {D. W.} and Park, {B. J.} and Lee, {I. S.} and Lee, {K. Y.} and Kim, {J. K.} and Hyon, {S. H.} and Park, {J. C.}",

year = "2004",

language = "English",

isbn = "1877040193",

series = "Transactions - 7th World Biomaterials Congress",

pages = "1203",

booktitle = "Transactions - 7th World Biomaterials Congress",

}

Han, DW, Park, BJ, Lee, IS, Lee, KY, Kim, JK, Hyon, SH & Park, JC 2004, Differential effects of green tea polyphenol on cellular responses in normal cells vs. cancer cells and its possible mechanisms. in Transactions - 7th World Biomaterials Congress. Transactions - 7th World Biomaterials Congress, pp. 1203, Transactions - 7th World Biomaterials Congress, Sydney, Australia, 04/5/17.

Differential effects of green tea polyphenol on cellular responses in normal cells vs. cancer cells and its possible mechanisms. / Han, D. W.; Park, B. J.; Lee, I. S.; Lee, K. Y.; Kim, J. K.; Hyon, S. H.; Park, J. C.

Transactions - 7th World Biomaterials Congress. 2004. p. 1203 (Transactions - 7th World Biomaterials Congress).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Differential effects of green tea polyphenol on cellular responses in normal cells vs. cancer cells and its possible mechanisms

AU - Han, D. W.

AU - Park, B. J.

AU - Lee, I. S.

AU - Lee, K. Y.

AU - Kim, J. K.

AU - Hyon, S. H.

AU - Park, J. C.

PY - 2004

Y1 - 2004

N2 - The differential biological responsiveness to green tea polyphenols (GTP) and inclusion of NF-kB as a mechanism in normal cells, immortalized cell line and cancer cells, was investigated. Cell growth, alkaline phosphatase (ALP) activity, DNA cell cycle and morphology were also analyzed. It was observed that at the higher dose of GTP, number of cells decreased. It was found that GTP imparted differential dose-based growth and function inhibitory responses toward the carcinoma cells as compared to the normal cells.

AB - The differential biological responsiveness to green tea polyphenols (GTP) and inclusion of NF-kB as a mechanism in normal cells, immortalized cell line and cancer cells, was investigated. Cell growth, alkaline phosphatase (ALP) activity, DNA cell cycle and morphology were also analyzed. It was observed that at the higher dose of GTP, number of cells decreased. It was found that GTP imparted differential dose-based growth and function inhibitory responses toward the carcinoma cells as compared to the normal cells.

UR - http://www.scopus.com/inward/record.url?scp=13844254040&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=13844254040&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:13844254040

SN - 1877040193

SN - 9781877040191

T3 - Transactions - 7th World Biomaterials Congress

SP - 1203

BT - Transactions - 7th World Biomaterials Congress

T2 - Transactions - 7th World Biomaterials Congress

Y2 - 17 May 2004 through 21 May 2004

ER -