Differentiation of indeterminate biliary stricture

Hong Jin Yoon, Sung Ill Jang, Dong Ki Lee

Research output: Chapter in Book/Report/Conference proceedingChapter


Preoperative evaluation of biliary strictures is problematic because of the risk of failing to detect a malignant tumor and the potential sequelae of unnecessary surgery in patients with strictures of benign origin. A stricture whose cause cannot be determined despite endoscopy, hematology, and imaging, including histological examination, is defined as an indeterminate biliary stricture. Imaging modalities-such as magnetic resonance imaging, magnetic resonance cholangiopancreatography, and multidetector computed tomography-play an important role in assessing the location, extent, length, and mass of the stricture. Early diagnosis of malignant strictures enables timely surgical intervention and administration of an appropriate chemotherapy regimen. However, no definitive diagnosis of malignant or benign strictures has been established. This chapter focuses on the causes of biliary strictures, and the blood tests, imaging studies, and endoscopic techniques that facilitate their diagnosis.

Original languageEnglish
Title of host publicationAdvanced ERCP for Complicated and Refractory Biliary and Pancreatic Diseases
PublisherSpringer Singapore
Number of pages15
ISBN (Electronic)9789811306082
ISBN (Print)9789811306075
Publication statusPublished - 2019 Jan 1

Bibliographical note

Publisher Copyright:
© Springer Nature Singapore Pte Ltd. 2020.

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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