Stochastic processes play a key role in the communications inside the cells, cell mitosis and membrane channel regulation. It has been suggested that the molecular transport mechanism can be based on rectified thermal diffusion in a Brownian ratchet. A two-dimensional optical potential of circular symmetry created by a Bessel light beam is an ideal playground to study these phenomena. This optical field can be tilted to create a periodic (washboard) potential of imperfect Brownian ratchet. The tilt variation induces a directed transport of microparticles or biomolecules across the potential barriers when biomolecules attached non-covalently to these microparticles. In the central maximum of Bessel beam particles can be guided due to radiation pressure. Our data offer a new venue for understanding of cooperative phenomena in biology.
|Title of host publication||European Conference on Biomedical Optics, ECBO 2003|
|Publisher||Optica Publishing Group (formerly OSA)|
|Number of pages||7|
|Publication status||Published - 2003|
|Event||European Conference on Biomedical Optics, ECBO 2003 - Munich, Germany|
Duration: 2003 Jun 22 → …
|Name||Optics InfoBase Conference Papers|
|Conference||European Conference on Biomedical Optics, ECBO 2003|
|Period||03/6/22 → …|
Bibliographical noteFunding Information:
We thank the UK Engineering and Physical Sciences Research Council for their support of this work and Lynn Paterson for chromosome samples preparations. We also thank Peter Bryant and Wilson Sibbett for fruitful discussion of our manuscript.
© 2003 SPIE-OSA.
All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Mechanics of Materials