Abstract
Background: Drusen are important risk factor for neovascular age-related macular degeneration (AMD) and have a dynamic nature as they can enlarge, newly form, or disappear over time. There have been few reports on drusen regression or choroidal neovascularization (CNV) development after macular hole surgery. We report, to our knowledge, the first case of both drusen regression and subsequent CNV development within 7 months of successful macular hole surgery. Case presentation: A 73-year-old woman presented with a stage 3 full-thickness macular hole and large, confluent soft macular drusen in the right eye and a neovascular age-related macular degeneration (AMD) in the fellow eye. Four months after the successful macular hole surgery, significant regression of drusen was seen, especially in the temporal area to the fovea. Three months later, the patient developed CNV and her best-corrected visual acuity decreased to 20/100, despite further regression of macular drusen. Conclusions: Macular hole patients with macular soft drusen need to be carefully followed up after surgery for possible drusen regression and CNV development.
| Original language | English |
|---|---|
| Article number | 43 |
| Journal | BMC Ophthalmology |
| Volume | 15 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2015 Apr 28 |
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All Science Journal Classification (ASJC) codes
- Ophthalmology
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Disappearance of soft drusen and subsequent development of choroidal neovascularization following macular hole surgery : A case report. / Lee, Ji Hwan; Lee, Taekjune; Lee, Sungchul; Lee, Christopher Seungkyu.
In: BMC Ophthalmology, Vol. 15, No. 1, 43, 28.04.2015.Research output: Contribution to journal › Article
TY - JOUR
T1 - Disappearance of soft drusen and subsequent development of choroidal neovascularization following macular hole surgery
T2 - A case report
AU - Lee, Ji Hwan
AU - Lee, Taekjune
AU - Lee, Sungchul
AU - Lee, Christopher Seungkyu
PY - 2015/4/28
Y1 - 2015/4/28
N2 - Background: Drusen are important risk factor for neovascular age-related macular degeneration (AMD) and have a dynamic nature as they can enlarge, newly form, or disappear over time. There have been few reports on drusen regression or choroidal neovascularization (CNV) development after macular hole surgery. We report, to our knowledge, the first case of both drusen regression and subsequent CNV development within 7 months of successful macular hole surgery. Case presentation: A 73-year-old woman presented with a stage 3 full-thickness macular hole and large, confluent soft macular drusen in the right eye and a neovascular age-related macular degeneration (AMD) in the fellow eye. Four months after the successful macular hole surgery, significant regression of drusen was seen, especially in the temporal area to the fovea. Three months later, the patient developed CNV and her best-corrected visual acuity decreased to 20/100, despite further regression of macular drusen. Conclusions: Macular hole patients with macular soft drusen need to be carefully followed up after surgery for possible drusen regression and CNV development.
AB - Background: Drusen are important risk factor for neovascular age-related macular degeneration (AMD) and have a dynamic nature as they can enlarge, newly form, or disappear over time. There have been few reports on drusen regression or choroidal neovascularization (CNV) development after macular hole surgery. We report, to our knowledge, the first case of both drusen regression and subsequent CNV development within 7 months of successful macular hole surgery. Case presentation: A 73-year-old woman presented with a stage 3 full-thickness macular hole and large, confluent soft macular drusen in the right eye and a neovascular age-related macular degeneration (AMD) in the fellow eye. Four months after the successful macular hole surgery, significant regression of drusen was seen, especially in the temporal area to the fovea. Three months later, the patient developed CNV and her best-corrected visual acuity decreased to 20/100, despite further regression of macular drusen. Conclusions: Macular hole patients with macular soft drusen need to be carefully followed up after surgery for possible drusen regression and CNV development.
UR - http://www.scopus.com/inward/record.url?scp=85018122151&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85018122151&partnerID=8YFLogxK
U2 - 10.1186/s12886-015-0029-8
DO - 10.1186/s12886-015-0029-8
M3 - Article
VL - 15
JO - BMC Ophthalmology
JF - BMC Ophthalmology
SN - 1471-2415
IS - 1
M1 - 43
ER -