Abstract
Novel artemisinin-glycolipid hybrids were directly synthesized from 12β (C-C)-type deoxoartemisinin and glycolipid and exhibited exceptional in vitro anticancer activity, particularly against the oral carcinoma cancer cell lines, respectively. The artemisinin-glycolipid hybrids, with effective concentrations under 20μM, demonstrated better anticancer activity than either artemisinin or glycolipid alone and showed five times more anti-oral cancer activity than either cisplatin or paclitaxel.
Original language | English |
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Pages (from-to) | 1471-1475 |
Number of pages | 5 |
Journal | Chemical and Pharmaceutical Bulletin |
Volume | 59 |
Issue number | 12 |
DOIs | |
Publication status | Published - 2011 |
All Science Journal Classification (ASJC) codes
- Chemistry(all)
- Drug Discovery