Disseminated infection due to mycobacterium avium subsp. avium in an Asian elephant (Elephas maximus)

Hwanyul Yong, Go Eun Choi, Byung Soo Lee, Jake Whang, Sung Jae Shin

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

A disseminated infection caused by Mycobacterium avium subspecies avium (MAA) was diagnosed in a 57-yr-old male Asian elephant (Elephas maximus) housed at the Seoul Zoo, Gyeonggi, Republic of Korea. An apparent granulomatous inflammation with central caseous necrosis was evident in the lung sections. To confirm mycobacterial infection, polymerase chain reactionrestriction enzyme polymorphism analysis (PCR-RFLP) of the rpoB and hsp65 genes was performed from multiple organs and cultured bacteria. The PCR-RFLP revealed a M. avium subspecies. MAA was identified by multiplex PCR for detection of IS901 and IS1311. Thus, it is believed that MAA caused the disseminated infection in this case. Although the source of infection was not determined, the elephant may have become infected through contamination of soil and feed by free-living birds infected with MAA. This is the first reported case of disseminated infection due to MAA in a captive elephant in the Republic of Korea.

Original languageEnglish
Pages (from-to)743-746
Number of pages4
JournalJournal of Zoo and Wildlife Medicine
Volume42
Issue number4
DOIs
Publication statusPublished - 2011 Dec

All Science Journal Classification (ASJC) codes

  • Animal Science and Zoology
  • veterinary(all)

Fingerprint Dive into the research topics of 'Disseminated infection due to mycobacterium avium subsp. avium in an Asian elephant (Elephas maximus)'. Together they form a unique fingerprint.

Cite this