Distinct releases of growth factors from three dimensional fibrous scaffolds combined with hydrogel for differentiation of mesenchymal stem cells

Hyun Jong Lee, Sangphil Park, Eunji Jang, Tae Geuk Lim, Sang Won Han, Hyue Won Lee, Ui Seok Chung, Won Gun Koh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

To mimic the actual microenvironment, independent release control of some growth factors is required in tissue engineering field. Here, we fabricated multifunctional nanofiber-based three dimensional (3D) cell scaffolds which have the capability of release of growth factors independently. From the osteogenesis differentiation of hMSC cultured on the fabricated scaffolds, the capacity as a tissue engineering scaffold was demonstrated successfully. We expect that this independently controlled release system has a great potential for tissue engineering, biochip and other biomedical fields.

Original languageEnglish
Title of host publicationProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
PublisherChemical and Biological Microsystems Society
Pages1705-1707
Number of pages3
ISBN (Print)9780979806452
Publication statusPublished - 2012 Jan 1
Event16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan
Duration: 2012 Oct 282012 Nov 1

Publication series

NameProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Other

Other16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
CountryJapan
CityOkinawa
Period12/10/2812/11/1

Fingerprint

Hydrogel
Stem cells
Tissue engineering
Hydrogels
Scaffolds
Intercellular Signaling Peptides and Proteins
Scaffolds (biology)
Tissue Scaffolds
Biochips
Bioelectric potentials
Nanofibers

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Cite this

Lee, H. J., Park, S., Jang, E., Lim, T. G., Won Han, S., Won Lee, H., ... Koh, W. G. (2012). Distinct releases of growth factors from three dimensional fibrous scaffolds combined with hydrogel for differentiation of mesenchymal stem cells. In Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 (pp. 1705-1707). (Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012). Chemical and Biological Microsystems Society.
Lee, Hyun Jong ; Park, Sangphil ; Jang, Eunji ; Lim, Tae Geuk ; Won Han, Sang ; Won Lee, Hyue ; Chung, Ui Seok ; Koh, Won Gun. / Distinct releases of growth factors from three dimensional fibrous scaffolds combined with hydrogel for differentiation of mesenchymal stem cells. Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Chemical and Biological Microsystems Society, 2012. pp. 1705-1707 (Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012).
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author = "Lee, {Hyun Jong} and Sangphil Park and Eunji Jang and Lim, {Tae Geuk} and {Won Han}, Sang and {Won Lee}, Hyue and Chung, {Ui Seok} and Koh, {Won Gun}",
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Lee, HJ, Park, S, Jang, E, Lim, TG, Won Han, S, Won Lee, H, Chung, US & Koh, WG 2012, Distinct releases of growth factors from three dimensional fibrous scaffolds combined with hydrogel for differentiation of mesenchymal stem cells. in Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012, Chemical and Biological Microsystems Society, pp. 1705-1707, 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012, Okinawa, Japan, 12/10/28.

Distinct releases of growth factors from three dimensional fibrous scaffolds combined with hydrogel for differentiation of mesenchymal stem cells. / Lee, Hyun Jong; Park, Sangphil; Jang, Eunji; Lim, Tae Geuk; Won Han, Sang; Won Lee, Hyue; Chung, Ui Seok; Koh, Won Gun.

Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Chemical and Biological Microsystems Society, 2012. p. 1705-1707 (Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Lee HJ, Park S, Jang E, Lim TG, Won Han S, Won Lee H et al. Distinct releases of growth factors from three dimensional fibrous scaffolds combined with hydrogel for differentiation of mesenchymal stem cells. In Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Chemical and Biological Microsystems Society. 2012. p. 1705-1707. (Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012).