Diverse left ventricular morphology and predictors of short-term outcome in patients with stress-induced cardiomyopathy

Sung Woo Kwon, Byung Ok Kim, Myung Hyun Kim, Sung Joo Lee, Ji Hyun Yoon, Hyemoon Chung, Chi Young Shim, Duk Kyu Cho, Sung Kee Ryu, Se Jung Yoon, Young Won Yoon, Hyuk Jae Chang, Se Joong Rim, Hyuck Moon Kwon, Yangsoo Jang, Bum Kee Hong

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Abstract

Background: There is paucity of data with regard to the clinical spectrum according to left ventricle (LV) morphological variation in stress-induced cardiomyopathy (SCMP) patients, and still there is controversy in terms of prognosis since some people believe that the published in-hospital mortality data of patients with SCMP are underestimated. Therefore, we sought to investigate the morphological features of LV and in-hospital outcome of patients with SCMP and explored predictors of short-term prognosis. Methods: This was a multicenter, observational study of 208 SCMP patients. Morphological features of LV were determined by echocardiography and were divided into typical (apical) and atypical ballooning types, which were subcategorized into mid-LV ballooning and basal 'inverted' ballooning type. All-cause mortality of patients with SCMP during hospitalization was recorded. Results: The apical ballooning type was most common (67.3%) in SCMP followed by the mid-LV ballooning type (28.3%), and the basal 'inverted' ballooning type (4.3%). There were no differences in stressor types and in-hospital mortality between patients with typical and atypical SCMP. Notably, all the in-hospital mortality of SCMP patients occurred in patients with physical stressors, where age, shock, and LV ejection fraction were the independent risk factors for predicting in-hospital mortality. Conclusions: SCMP patients showed diverse patterns of LV morphology, but there were no definite differences on clinical spectrum among SCMP patients presenting various LV morphological patterns. In terms of short-term prognosis, underlying physical conditions combined with old age, hemodynamic compromise, and low LV systolic function might be the most important factors in SCMP patients.

Original languageEnglish
Pages (from-to)331-337
Number of pages7
JournalInternational Journal of Cardiology
Volume168
Issue number1
DOIs
Publication statusPublished - 2013 Sep 20

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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    Kwon, S. W., Kim, B. O., Kim, M. H., Lee, S. J., Yoon, J. H., Chung, H., Shim, C. Y., Cho, D. K., Ryu, S. K., Yoon, S. J., Yoon, Y. W., Chang, H. J., Rim, S. J., Kwon, H. M., Jang, Y., & Hong, B. K. (2013). Diverse left ventricular morphology and predictors of short-term outcome in patients with stress-induced cardiomyopathy. International Journal of Cardiology, 168(1), 331-337. https://doi.org/10.1016/j.ijcard.2012.09.050