Diversity-oriented functionalization of indolizines at the C3 position via multicomponent Kabachnik-Fields reaction

Jinwoo Kim, Yunkyung Heo, Youngeun Jung, Jinu Lee, Ikyon Kim

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A diversity-oriented approach to new indolizines highly functionalized at the C3 position was achieved by using the Kabachnik-Fields three-component reaction. Some of the synthesized compounds exhibited a significant gap junction inhibitory activity.

Original languageEnglish
Pages (from-to)5759-5768
Number of pages10
JournalTetrahedron
Volume73
Issue number39
DOIs
Publication statusPublished - 2017 Jan 1

Fingerprint

Indolizines
Gap Junctions

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

@article{39cb893ed54c4531bd6dc0098ba671d7,
title = "Diversity-oriented functionalization of indolizines at the C3 position via multicomponent Kabachnik-Fields reaction",
abstract = "A diversity-oriented approach to new indolizines highly functionalized at the C3 position was achieved by using the Kabachnik-Fields three-component reaction. Some of the synthesized compounds exhibited a significant gap junction inhibitory activity.",
author = "Jinwoo Kim and Yunkyung Heo and Youngeun Jung and Jinu Lee and Ikyon Kim",
year = "2017",
month = "1",
day = "1",
doi = "10.1016/j.tet.2017.08.017",
language = "English",
volume = "73",
pages = "5759--5768",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Limited",
number = "39",

}

Diversity-oriented functionalization of indolizines at the C3 position via multicomponent Kabachnik-Fields reaction. / Kim, Jinwoo; Heo, Yunkyung; Jung, Youngeun; Lee, Jinu; Kim, Ikyon.

In: Tetrahedron, Vol. 73, No. 39, 01.01.2017, p. 5759-5768.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Diversity-oriented functionalization of indolizines at the C3 position via multicomponent Kabachnik-Fields reaction

AU - Kim, Jinwoo

AU - Heo, Yunkyung

AU - Jung, Youngeun

AU - Lee, Jinu

AU - Kim, Ikyon

PY - 2017/1/1

Y1 - 2017/1/1

N2 - A diversity-oriented approach to new indolizines highly functionalized at the C3 position was achieved by using the Kabachnik-Fields three-component reaction. Some of the synthesized compounds exhibited a significant gap junction inhibitory activity.

AB - A diversity-oriented approach to new indolizines highly functionalized at the C3 position was achieved by using the Kabachnik-Fields three-component reaction. Some of the synthesized compounds exhibited a significant gap junction inhibitory activity.

UR - http://www.scopus.com/inward/record.url?scp=85027985887&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85027985887&partnerID=8YFLogxK

U2 - 10.1016/j.tet.2017.08.017

DO - 10.1016/j.tet.2017.08.017

M3 - Article

AN - SCOPUS:85027985887

VL - 73

SP - 5759

EP - 5768

JO - Tetrahedron

JF - Tetrahedron

SN - 0040-4020

IS - 39

ER -