Diversity-oriented functionalization of indolizines at the C3 position via multicomponent Kabachnik-Fields reaction

Jinwoo Kim, Yunkyung Heo, Youngeun Jung, Jinu Lee, Ikyon Kim

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7 Citations (Scopus)

Abstract

A diversity-oriented approach to new indolizines highly functionalized at the C3 position was achieved by using the Kabachnik-Fields three-component reaction. Some of the synthesized compounds exhibited a significant gap junction inhibitory activity.

Original languageEnglish
Pages (from-to)5759-5768
Number of pages10
JournalTetrahedron
Volume73
Issue number39
DOIs
Publication statusPublished - 2017

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) ( 2014R1A2A1A11050491 ) (to I. K.) and by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education ( 2016R1D1A1A02937397 ) (to J. L.). Appendix A

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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