Do different arterial stiffness parameters provide similar information in high-risk patients for coronary artery disease?

Kyung Min Kim, Byung Su Yoo, Anna Ko, Jeong Min Kim, Hyun Sik Kim, Jun Won Lee, Jang Young Kim, G. Jin Youn, Sung Gyun Ahn, Seung Hwan Lee, Junghan Yoon

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background and Objectives: The aim of our study was to compare the values of brachial-ankle pulse wave velocity (baPWV) measured with two different non-invasive methods as predictors of coronary artery disease CAD in patients who had undergone coronary angiography. Subjects and Methods: From 6373 patients who visited our laboratory for non-invasive procedures, we enrolled 965 consecutive patients undergoing coronary angiography. Data for baPWV and peripheral augmentation index pAI were recorded. CAD was defined as greater than 50% stenosis of a major epicardial artery in a coronary angiogram. In addition, the severity of CAD was classified as: none/ minimal or 1-, 2-, or 3-vessel disease, based on previous or current angiographic findings. Results: Among 965 subjects, the mean age was 63.7±11.6 years, and 58.2% were male. Compared with subjects without CAD disease, those with CAD showed higher values of baPWV (16.6±3.5 m/sec vs. 15.9±3.4 m/sec, pcO.001), and lower values of pAI (73.5±15.9% vs. 76.0±15.7%, p=0.01 ). When the severity of CAD was expressed as none/minimal or 1-, 2-, or 3-vessel disease, there was a significant association between the extent of CAD and baPWV (p<0.00l). In univariate analysis, high PWV and low pAI were associated with an increased prevalence of CAD (p<0.00l). Conclusion: Increased baPWV and decreased pAI were associated with the presence of CAD in the elderly.

Original languageEnglish
Pages (from-to)819-824
Number of pages6
JournalKorean Circulation Journal
Volume43
Issue number12
DOIs
Publication statusPublished - 2013 Dec 1

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

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