Does post-biopsy mammography at short-term interval contribute to early detection of cancer in patients diagnosed with benign-concordant microcalcifications on stereotactic biopsy?

Go Eun Yang, Eun Kyung Kim, Min Jung Kim, Hee Jung Moon, Vivian Youngjean Park, Jung Hyun Yoon

Research output: Contribution to journalArticle

Abstract

Background: Currently, there are no strict post-biopsy guidelines for managing stereotactic biopsy-proven benign lesions manifesting as microcalcifications on mammography without an accompanying mass. Objectives: To evaluate whether short-term follow-up mammography contributes to the detection of early cancer for patients with microcalcification-only lesions that were diagnosed as benign stereotactic biopsy. Patients and Methods: Two-hundred sixty-two microcalcification-only lesions in 259 women (mean age: 47.7 years) who were diagnosed as benign on stereotactic biopsy and been followed with mammography for at least 2 years were included. Serial mammograms were reviewed from the initial pre-biopsy mammograms to the most recent examination. Mammographic findings were designated as stable, decreased, or newly developed microcalcifications. Medical records of each patient were reviewed for clinical information and pathology results of additional biopsy or surgical procedures. Results: Of the 262 microcalcifications diagnosed as benign on stereotactic biopsy, 258 (98.5%) were finally diagnosed as benign, one (0.4%) as high-risk lesion, and three (1.1%) as malignant. The three cancers were all diagnosed as ductal carcinoma in situ (DCIS) at 31, 36 and 6 months after initial biopsy. The DCIS diagnosed at 6 months post-biopsy had no mammographic changes, and was detected on breast ultrasonography, while the remaining two cases had no detectable findings on the short-term follow-up mammography. Conclusion: Short-term follow-up mammography did not contribute in detecting additional breast cancers, and may have a limited role in patients diagnosed with benign-concordant microcalcifications on large-bore stereotactic biopsy.

Original languageEnglish
Article numbere74248
JournalIranian Journal of Radiology
Volume16
Issue number3
DOIs
Publication statusPublished - 2019 Jul

Fingerprint

Calcinosis
Mammography
Early Detection of Cancer
Biopsy
Carcinoma, Intraductal, Noninfiltrating
Mammary Ultrasonography
Clinical Pathology
Medical Records
Guidelines
Breast Neoplasms

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

@article{fc34400a51dc46b795817e5caeaadd5b,
title = "Does post-biopsy mammography at short-term interval contribute to early detection of cancer in patients diagnosed with benign-concordant microcalcifications on stereotactic biopsy?",
abstract = "Background: Currently, there are no strict post-biopsy guidelines for managing stereotactic biopsy-proven benign lesions manifesting as microcalcifications on mammography without an accompanying mass. Objectives: To evaluate whether short-term follow-up mammography contributes to the detection of early cancer for patients with microcalcification-only lesions that were diagnosed as benign stereotactic biopsy. Patients and Methods: Two-hundred sixty-two microcalcification-only lesions in 259 women (mean age: 47.7 years) who were diagnosed as benign on stereotactic biopsy and been followed with mammography for at least 2 years were included. Serial mammograms were reviewed from the initial pre-biopsy mammograms to the most recent examination. Mammographic findings were designated as stable, decreased, or newly developed microcalcifications. Medical records of each patient were reviewed for clinical information and pathology results of additional biopsy or surgical procedures. Results: Of the 262 microcalcifications diagnosed as benign on stereotactic biopsy, 258 (98.5{\%}) were finally diagnosed as benign, one (0.4{\%}) as high-risk lesion, and three (1.1{\%}) as malignant. The three cancers were all diagnosed as ductal carcinoma in situ (DCIS) at 31, 36 and 6 months after initial biopsy. The DCIS diagnosed at 6 months post-biopsy had no mammographic changes, and was detected on breast ultrasonography, while the remaining two cases had no detectable findings on the short-term follow-up mammography. Conclusion: Short-term follow-up mammography did not contribute in detecting additional breast cancers, and may have a limited role in patients diagnosed with benign-concordant microcalcifications on large-bore stereotactic biopsy.",
author = "Yang, {Go Eun} and Kim, {Eun Kyung} and Kim, {Min Jung} and Moon, {Hee Jung} and Park, {Vivian Youngjean} and Yoon, {Jung Hyun}",
year = "2019",
month = "7",
doi = "10.5812/iranjradiol.74248",
language = "English",
volume = "16",
journal = "Iranian Journal of Radiology",
issn = "1735-1065",
publisher = "Kowsar Publishing Company",
number = "3",

}

Does post-biopsy mammography at short-term interval contribute to early detection of cancer in patients diagnosed with benign-concordant microcalcifications on stereotactic biopsy? / Yang, Go Eun; Kim, Eun Kyung; Kim, Min Jung; Moon, Hee Jung; Park, Vivian Youngjean; Yoon, Jung Hyun.

In: Iranian Journal of Radiology, Vol. 16, No. 3, e74248, 07.2019.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Does post-biopsy mammography at short-term interval contribute to early detection of cancer in patients diagnosed with benign-concordant microcalcifications on stereotactic biopsy?

AU - Yang, Go Eun

AU - Kim, Eun Kyung

AU - Kim, Min Jung

AU - Moon, Hee Jung

AU - Park, Vivian Youngjean

AU - Yoon, Jung Hyun

PY - 2019/7

Y1 - 2019/7

N2 - Background: Currently, there are no strict post-biopsy guidelines for managing stereotactic biopsy-proven benign lesions manifesting as microcalcifications on mammography without an accompanying mass. Objectives: To evaluate whether short-term follow-up mammography contributes to the detection of early cancer for patients with microcalcification-only lesions that were diagnosed as benign stereotactic biopsy. Patients and Methods: Two-hundred sixty-two microcalcification-only lesions in 259 women (mean age: 47.7 years) who were diagnosed as benign on stereotactic biopsy and been followed with mammography for at least 2 years were included. Serial mammograms were reviewed from the initial pre-biopsy mammograms to the most recent examination. Mammographic findings were designated as stable, decreased, or newly developed microcalcifications. Medical records of each patient were reviewed for clinical information and pathology results of additional biopsy or surgical procedures. Results: Of the 262 microcalcifications diagnosed as benign on stereotactic biopsy, 258 (98.5%) were finally diagnosed as benign, one (0.4%) as high-risk lesion, and three (1.1%) as malignant. The three cancers were all diagnosed as ductal carcinoma in situ (DCIS) at 31, 36 and 6 months after initial biopsy. The DCIS diagnosed at 6 months post-biopsy had no mammographic changes, and was detected on breast ultrasonography, while the remaining two cases had no detectable findings on the short-term follow-up mammography. Conclusion: Short-term follow-up mammography did not contribute in detecting additional breast cancers, and may have a limited role in patients diagnosed with benign-concordant microcalcifications on large-bore stereotactic biopsy.

AB - Background: Currently, there are no strict post-biopsy guidelines for managing stereotactic biopsy-proven benign lesions manifesting as microcalcifications on mammography without an accompanying mass. Objectives: To evaluate whether short-term follow-up mammography contributes to the detection of early cancer for patients with microcalcification-only lesions that were diagnosed as benign stereotactic biopsy. Patients and Methods: Two-hundred sixty-two microcalcification-only lesions in 259 women (mean age: 47.7 years) who were diagnosed as benign on stereotactic biopsy and been followed with mammography for at least 2 years were included. Serial mammograms were reviewed from the initial pre-biopsy mammograms to the most recent examination. Mammographic findings were designated as stable, decreased, or newly developed microcalcifications. Medical records of each patient were reviewed for clinical information and pathology results of additional biopsy or surgical procedures. Results: Of the 262 microcalcifications diagnosed as benign on stereotactic biopsy, 258 (98.5%) were finally diagnosed as benign, one (0.4%) as high-risk lesion, and three (1.1%) as malignant. The three cancers were all diagnosed as ductal carcinoma in situ (DCIS) at 31, 36 and 6 months after initial biopsy. The DCIS diagnosed at 6 months post-biopsy had no mammographic changes, and was detected on breast ultrasonography, while the remaining two cases had no detectable findings on the short-term follow-up mammography. Conclusion: Short-term follow-up mammography did not contribute in detecting additional breast cancers, and may have a limited role in patients diagnosed with benign-concordant microcalcifications on large-bore stereotactic biopsy.

UR - http://www.scopus.com/inward/record.url?scp=85069852724&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85069852724&partnerID=8YFLogxK

U2 - 10.5812/iranjradiol.74248

DO - 10.5812/iranjradiol.74248

M3 - Article

AN - SCOPUS:85069852724

VL - 16

JO - Iranian Journal of Radiology

JF - Iranian Journal of Radiology

SN - 1735-1065

IS - 3

M1 - e74248

ER -