Draft genome sequence of Streptomyces clavuligerus NRRL 3585, a producer of diverse secondary metabolites

Ju Yeon Song, Haeyoung Jeong, Dong Su Yu, Michael A. Fischbach, Hong Seog Park, Jae Jong Kim, Jeong Sun Seo, Susan E. Jensen, Tae Kwang Oh, Kye Joon Lee, Jihyun F. Kim

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40 Citations (Scopus)

Abstract

Streptomyces clavuligerus is an important industrial strain that produces a number of antibiotics, including clavulanic acid and cephamycin C. A high-quality draft genome sequence of the S. clavuligerus NRRL 3585 strain was produced by employing a hybrid approach that involved Sanger sequencing, Roche/454 pyrose-quencing, optical mapping, and partial finishing. Its genome, comprising four linear replicons, one chromosome, and four plasmids, carries numerous sets of genes involved in the biosynthesis of secondary metabolites, including a variety of antibiotics.

Original languageEnglish
Pages (from-to)6317-6318
Number of pages2
JournalJournal of Bacteriology
Volume192
Issue number23
DOIs
Publication statusPublished - 2010 Dec

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Molecular Biology

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    Song, J. Y., Jeong, H., Yu, D. S., Fischbach, M. A., Park, H. S., Kim, J. J., Seo, J. S., Jensen, S. E., Oh, T. K., Lee, K. J., & Kim, J. F. (2010). Draft genome sequence of Streptomyces clavuligerus NRRL 3585, a producer of diverse secondary metabolites. Journal of Bacteriology, 192(23), 6317-6318. https://doi.org/10.1128/JB.00859-10