Drawing sticky adeno-associated viruses on surfaces for spatially patterned gene expression

Eunmi Kim; In Taek Song; Slgirim Lee; Jung Suk Kim; Haeshin Lee; Jae Hyung Jang

doi:10.1002/anie.201201495

Drawing sticky adeno-associated viruses on surfaces for spatially patterned gene expression

Eunmi Kim, In Taek Song, Slgirim Lee, Jung Suk Kim, Haeshin Lee, Jae Hyung Jang

Department of Chemical and Biomolecular Engineering

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

Sticky stuff: A versatile strategy to spatially control gene expressions of mammalian cells is developed. A catecholamine polymer (PEI-C) is used to functionalize surfaces of adeno-associated viruses (AAV). Because of the underwater adhesive property of catechol, AAV/PEI-C hybrid vectors become highly "sticky", resulting in spatially patterned viral attachment onto substrates by the simple "gene-vector drawing" technique (see picture).

Original language	English
Pages (from-to)	5598-5601
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	51
Issue number	23
DOIs	https://doi.org/10.1002/anie.201201495
Publication status	Published - 2012 Jun 4

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)

Access to Document

10.1002/anie.201201495

Cite this

@article{6a07771bbc164200a7ea8b6002f8e1b2,

title = "Drawing sticky adeno-associated viruses on surfaces for spatially patterned gene expression",

abstract = "Sticky stuff: A versatile strategy to spatially control gene expressions of mammalian cells is developed. A catecholamine polymer (PEI-C) is used to functionalize surfaces of adeno-associated viruses (AAV). Because of the underwater adhesive property of catechol, AAV/PEI-C hybrid vectors become highly {"}sticky{"}, resulting in spatially patterned viral attachment onto substrates by the simple {"}gene-vector drawing{"} technique (see picture).",

author = "Eunmi Kim and Song, {In Taek} and Slgirim Lee and Kim, {Jung Suk} and Haeshin Lee and Jang, {Jae Hyung}",

year = "2012",

month = jun,

day = "4",

doi = "10.1002/anie.201201495",

language = "English",

volume = "51",

pages = "5598--5601",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "23",

}

TY - JOUR

T1 - Drawing sticky adeno-associated viruses on surfaces for spatially patterned gene expression

AU - Kim, Eunmi

AU - Song, In Taek

AU - Lee, Slgirim

AU - Kim, Jung Suk

AU - Lee, Haeshin

AU - Jang, Jae Hyung

PY - 2012/6/4

Y1 - 2012/6/4

N2 - Sticky stuff: A versatile strategy to spatially control gene expressions of mammalian cells is developed. A catecholamine polymer (PEI-C) is used to functionalize surfaces of adeno-associated viruses (AAV). Because of the underwater adhesive property of catechol, AAV/PEI-C hybrid vectors become highly "sticky", resulting in spatially patterned viral attachment onto substrates by the simple "gene-vector drawing" technique (see picture).

AB - Sticky stuff: A versatile strategy to spatially control gene expressions of mammalian cells is developed. A catecholamine polymer (PEI-C) is used to functionalize surfaces of adeno-associated viruses (AAV). Because of the underwater adhesive property of catechol, AAV/PEI-C hybrid vectors become highly "sticky", resulting in spatially patterned viral attachment onto substrates by the simple "gene-vector drawing" technique (see picture).

UR - http://www.scopus.com/inward/record.url?scp=84861618518&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861618518&partnerID=8YFLogxK

U2 - 10.1002/anie.201201495

DO - 10.1002/anie.201201495

M3 - Article

C2 - 22539413

AN - SCOPUS:84861618518

VL - 51

SP - 5598

EP - 5601

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

SN - 1433-7851

IS - 23

ER -

Drawing sticky adeno-associated viruses on surfaces for spatially patterned gene expression

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this