Abstract
Sticky stuff: A versatile strategy to spatially control gene expressions of mammalian cells is developed. A catecholamine polymer (PEI-C) is used to functionalize surfaces of adeno-associated viruses (AAV). Because of the underwater adhesive property of catechol, AAV/PEI-C hybrid vectors become highly "sticky", resulting in spatially patterned viral attachment onto substrates by the simple "gene-vector drawing" technique (see picture).
| Original language | English |
|---|---|
| Pages (from-to) | 5598-5601 |
| Number of pages | 4 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 51 |
| Issue number | 23 |
| DOIs | |
| Publication status | Published - 2012 Jun 4 |
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All Science Journal Classification (ASJC) codes
- Catalysis
- Chemistry(all)
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Drawing sticky adeno-associated viruses on surfaces for spatially patterned gene expression. / Kim, Eunmi; Song, In Taek; Lee, Slgirim; Kim, Jung Suk; Lee, Haeshin; Jang, Jae Hyung.
In: Angewandte Chemie - International Edition, Vol. 51, No. 23, 04.06.2012, p. 5598-5601.Research output: Contribution to journal › Article
TY - JOUR
T1 - Drawing sticky adeno-associated viruses on surfaces for spatially patterned gene expression
AU - Kim, Eunmi
AU - Song, In Taek
AU - Lee, Slgirim
AU - Kim, Jung Suk
AU - Lee, Haeshin
AU - Jang, Jae Hyung
PY - 2012/6/4
Y1 - 2012/6/4
N2 - Sticky stuff: A versatile strategy to spatially control gene expressions of mammalian cells is developed. A catecholamine polymer (PEI-C) is used to functionalize surfaces of adeno-associated viruses (AAV). Because of the underwater adhesive property of catechol, AAV/PEI-C hybrid vectors become highly "sticky", resulting in spatially patterned viral attachment onto substrates by the simple "gene-vector drawing" technique (see picture).
AB - Sticky stuff: A versatile strategy to spatially control gene expressions of mammalian cells is developed. A catecholamine polymer (PEI-C) is used to functionalize surfaces of adeno-associated viruses (AAV). Because of the underwater adhesive property of catechol, AAV/PEI-C hybrid vectors become highly "sticky", resulting in spatially patterned viral attachment onto substrates by the simple "gene-vector drawing" technique (see picture).
UR - http://www.scopus.com/inward/record.url?scp=84861618518&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84861618518&partnerID=8YFLogxK
U2 - 10.1002/anie.201201495
DO - 10.1002/anie.201201495
M3 - Article
C2 - 22539413
AN - SCOPUS:84861618518
VL - 51
SP - 5598
EP - 5601
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
SN - 1433-7851
IS - 23
ER -