Dual changes in conformation and optical properties of fluorophores within a metal-organic framework during framework construction and associated sensing event

Won Cho, Hee Jung Lee, Goeun Choi, Sora Choi, Moonhyun Oh

Research output: Contribution to journalArticle

88 Citations (Scopus)

Abstract

Microsized chemosensor particle (CPP-16, CPP means coordination polymer particle), which is made from a metal-organic framework (MOF), is synthesized using pyrene-functionalized organic building block. This building block contains three important parts, a framework construction part, a Cu 2+ detection part, and a fluorophore part. PXRD studies have revealed that CPP-16 has a 3D cubic structure of MOF-5. During both MOF formation and sensing event, fluorophores within CPP-16 undergo dual changes in conformation and optical properties. After MOF construction, pyrene moieties experience an unusual complete conversion from monomer to excimer form. This conversion takes place due to a confinement effect induced by space limitations within the MOF structure. The selective sensing ability of CPP-16 on Cu 2+ over many other metal ions is verified by emission spectra and is also visually identified by fluorescence microscopy images. Specific interaction of Cu 2+ with binding sites within CPP-16 causes a second conformational change of the fluorophores, where they change from stacked excimer (CPP-16) to quenched excimer states (CPP-16·Cu 2+ ).

Original languageEnglish
Pages (from-to)12201-12204
Number of pages4
JournalJournal of the American Chemical Society
Volume136
Issue number35
DOIs
Publication statusPublished - 2014 Sep 3

Fingerprint

Fluorophores
Conformations
Optical properties
Metals
Pyrene
Fluorescence microscopy
Binding sites
Metal ions
Monomers
3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid
Fluorescence Microscopy
Polymers
Binding Sites
Ions

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

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title = "Dual changes in conformation and optical properties of fluorophores within a metal-organic framework during framework construction and associated sensing event",
abstract = "Microsized chemosensor particle (CPP-16, CPP means coordination polymer particle), which is made from a metal-organic framework (MOF), is synthesized using pyrene-functionalized organic building block. This building block contains three important parts, a framework construction part, a Cu 2+ detection part, and a fluorophore part. PXRD studies have revealed that CPP-16 has a 3D cubic structure of MOF-5. During both MOF formation and sensing event, fluorophores within CPP-16 undergo dual changes in conformation and optical properties. After MOF construction, pyrene moieties experience an unusual complete conversion from monomer to excimer form. This conversion takes place due to a confinement effect induced by space limitations within the MOF structure. The selective sensing ability of CPP-16 on Cu 2+ over many other metal ions is verified by emission spectra and is also visually identified by fluorescence microscopy images. Specific interaction of Cu 2+ with binding sites within CPP-16 causes a second conformational change of the fluorophores, where they change from stacked excimer (CPP-16) to quenched excimer states (CPP-16·Cu 2+ ).",
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Dual changes in conformation and optical properties of fluorophores within a metal-organic framework during framework construction and associated sensing event. / Cho, Won; Lee, Hee Jung; Choi, Goeun; Choi, Sora; Oh, Moonhyun.

In: Journal of the American Chemical Society, Vol. 136, No. 35, 03.09.2014, p. 12201-12204.

Research output: Contribution to journalArticle

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