Ductal eccrine carcinoma presenting as a Paget's disease-like lesion of the breast

Byeong Woo Park, Seung Il Kim, Kyong Sik Lee, Woo Ick Yang

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4 Citations (Scopus)


Some types of skin appendage tumors, particularly ductal eccrine carcinomas (DEC), imitate breast carcinomas histologically, thus causing great diagnostic challenges. We describe a case of DEC presenting as an eczematous, crusted skin lesion on the right nipple-areolar complex in a 67-year-old woman. A skin biopsy done under the clinical impression of Paget's disease of the nipple was initially misinterpreted as infiltrating ductal carcinoma, and a subsequent modified radical mastectomy revealed DEC exclusively confined to the nipple with perinodal tumor metastasis in one of the axillary lymph nodes. This case highlights the diagnostic difficulty caused by the histologic homology between breast carcinomas and skin appendage tumors with ductal differentiation.

Original languageEnglish
Pages (from-to)358-362
Number of pages5
JournalBreast Journal
Issue number5
Publication statusPublished - 2001 Dec 11


All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Surgery
  • Oncology

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