Dynamic patterns of PTK7 protein expression in adult mouse tissues

Jihee Kim, Ho Yoon, Song Ee Lee, Won Suk Kang, Iksoo Jeon, Da Jeong Chang, Nayeon Lee, Taesun Hwang, Won Sik Shin, Han Woong Lee, Seung Taek Lee, Jihwan Song

Research output: Contribution to journalArticle

Abstract

PTK7 belongs to a subgroup of receptor protein tyrosine kinases with inactive catalytic activity of the protein tyrosine kinase(PTK), which is known to be important for signal attenuation, cell adhesion, and regulation of planar cell polarity. In this study, to decipher possible biological roles of PTK7, we examined the tissue distribution and localization of PTK7 protein in adult mouse tissues. PTK7-positive signals were detected in variety of tissues and cells in multiple systems, including respiratory, digestive, urinary and reproductive organs, as well as liver and pancreas. These expression profiling data imply various physiological roles of PTK7 in multiple organ systems. Interestingly, among various tissues examined, no specific signal was detected in the heart and muscles. Taken together, dynamic patterns of protein expression in adult tissues strongly suggest PTK7 may play important roles during organogenesis and histogenesis.

Original languageEnglish
Pages (from-to)885-888
Number of pages4
JournalTissue Engineering and Regenerative Medicine
Volume5
Issue number4-6
Publication statusPublished - 2008 Dec 1

Fingerprint

Tissue
Proteins
Cell Polarity
Organogenesis
Respiratory system
Receptor Protein-Tyrosine Kinases
Tissue Distribution
Cell Adhesion
Respiratory System
Protein-Tyrosine Kinases
Cell adhesion
Pancreas
Myocardium
Liver
Muscle
Catalyst activity
Cells

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Biomedical Engineering

Cite this

Kim, J., Yoon, H., Lee, S. E., Kang, W. S., Jeon, I., Chang, D. J., ... Song, J. (2008). Dynamic patterns of PTK7 protein expression in adult mouse tissues. Tissue Engineering and Regenerative Medicine, 5(4-6), 885-888.
Kim, Jihee ; Yoon, Ho ; Lee, Song Ee ; Kang, Won Suk ; Jeon, Iksoo ; Chang, Da Jeong ; Lee, Nayeon ; Hwang, Taesun ; Shin, Won Sik ; Lee, Han Woong ; Lee, Seung Taek ; Song, Jihwan. / Dynamic patterns of PTK7 protein expression in adult mouse tissues. In: Tissue Engineering and Regenerative Medicine. 2008 ; Vol. 5, No. 4-6. pp. 885-888.
@article{715d996749644834a6ec3ed4a45536ef,
title = "Dynamic patterns of PTK7 protein expression in adult mouse tissues",
abstract = "PTK7 belongs to a subgroup of receptor protein tyrosine kinases with inactive catalytic activity of the protein tyrosine kinase(PTK), which is known to be important for signal attenuation, cell adhesion, and regulation of planar cell polarity. In this study, to decipher possible biological roles of PTK7, we examined the tissue distribution and localization of PTK7 protein in adult mouse tissues. PTK7-positive signals were detected in variety of tissues and cells in multiple systems, including respiratory, digestive, urinary and reproductive organs, as well as liver and pancreas. These expression profiling data imply various physiological roles of PTK7 in multiple organ systems. Interestingly, among various tissues examined, no specific signal was detected in the heart and muscles. Taken together, dynamic patterns of protein expression in adult tissues strongly suggest PTK7 may play important roles during organogenesis and histogenesis.",
author = "Jihee Kim and Ho Yoon and Lee, {Song Ee} and Kang, {Won Suk} and Iksoo Jeon and Chang, {Da Jeong} and Nayeon Lee and Taesun Hwang and Shin, {Won Sik} and Lee, {Han Woong} and Lee, {Seung Taek} and Jihwan Song",
year = "2008",
month = "12",
day = "1",
language = "English",
volume = "5",
pages = "885--888",
journal = "Tissue Engineering and Regenerative Medicine",
issn = "1738-2696",
publisher = "Springer Science + Business Media",
number = "4-6",

}

Kim, J, Yoon, H, Lee, SE, Kang, WS, Jeon, I, Chang, DJ, Lee, N, Hwang, T, Shin, WS, Lee, HW, Lee, ST & Song, J 2008, 'Dynamic patterns of PTK7 protein expression in adult mouse tissues', Tissue Engineering and Regenerative Medicine, vol. 5, no. 4-6, pp. 885-888.

Dynamic patterns of PTK7 protein expression in adult mouse tissues. / Kim, Jihee; Yoon, Ho; Lee, Song Ee; Kang, Won Suk; Jeon, Iksoo; Chang, Da Jeong; Lee, Nayeon; Hwang, Taesun; Shin, Won Sik; Lee, Han Woong; Lee, Seung Taek; Song, Jihwan.

In: Tissue Engineering and Regenerative Medicine, Vol. 5, No. 4-6, 01.12.2008, p. 885-888.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Dynamic patterns of PTK7 protein expression in adult mouse tissues

AU - Kim, Jihee

AU - Yoon, Ho

AU - Lee, Song Ee

AU - Kang, Won Suk

AU - Jeon, Iksoo

AU - Chang, Da Jeong

AU - Lee, Nayeon

AU - Hwang, Taesun

AU - Shin, Won Sik

AU - Lee, Han Woong

AU - Lee, Seung Taek

AU - Song, Jihwan

PY - 2008/12/1

Y1 - 2008/12/1

N2 - PTK7 belongs to a subgroup of receptor protein tyrosine kinases with inactive catalytic activity of the protein tyrosine kinase(PTK), which is known to be important for signal attenuation, cell adhesion, and regulation of planar cell polarity. In this study, to decipher possible biological roles of PTK7, we examined the tissue distribution and localization of PTK7 protein in adult mouse tissues. PTK7-positive signals were detected in variety of tissues and cells in multiple systems, including respiratory, digestive, urinary and reproductive organs, as well as liver and pancreas. These expression profiling data imply various physiological roles of PTK7 in multiple organ systems. Interestingly, among various tissues examined, no specific signal was detected in the heart and muscles. Taken together, dynamic patterns of protein expression in adult tissues strongly suggest PTK7 may play important roles during organogenesis and histogenesis.

AB - PTK7 belongs to a subgroup of receptor protein tyrosine kinases with inactive catalytic activity of the protein tyrosine kinase(PTK), which is known to be important for signal attenuation, cell adhesion, and regulation of planar cell polarity. In this study, to decipher possible biological roles of PTK7, we examined the tissue distribution and localization of PTK7 protein in adult mouse tissues. PTK7-positive signals were detected in variety of tissues and cells in multiple systems, including respiratory, digestive, urinary and reproductive organs, as well as liver and pancreas. These expression profiling data imply various physiological roles of PTK7 in multiple organ systems. Interestingly, among various tissues examined, no specific signal was detected in the heart and muscles. Taken together, dynamic patterns of protein expression in adult tissues strongly suggest PTK7 may play important roles during organogenesis and histogenesis.

UR - http://www.scopus.com/inward/record.url?scp=84884542045&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84884542045&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84884542045

VL - 5

SP - 885

EP - 888

JO - Tissue Engineering and Regenerative Medicine

JF - Tissue Engineering and Regenerative Medicine

SN - 1738-2696

IS - 4-6

ER -

Kim J, Yoon H, Lee SE, Kang WS, Jeon I, Chang DJ et al. Dynamic patterns of PTK7 protein expression in adult mouse tissues. Tissue Engineering and Regenerative Medicine. 2008 Dec 1;5(4-6):885-888.