Early caries detection methods according to the depth of the lesion: An in vitro comparison

Hee Eun Kim, Baek Il Kim

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Purpose: The aims of this study were to estimate the histological and optical changes of early carious lesions according to the duration of demineralization and to compare the efficacy to detect early carious lesions of a quantitative light-induced fluorescence (QLF) system with a spectrophotometer according to the lesion depth. Methods: Eighty-four bovine enamel specimens were immersed in demineralizing gel for six distinct days. The severities of lesions were evaluated by lesion depths (Ld) by polarized light microscopy, fluorescence loss (ΔF) using QLF, and brightness (ΔL*) by spectrophotometry. The relationships between Ld, ΔF, and ΔL*were analyzed. Results and conclusion: Ld tended to be significantly deeper according to the demineralizing period (p < 0.05). The ΔF significantly decreased (p < 0.05) and the ΔL* significantly increased with increasing the demineralizing period (p < 0.05). More shallow lesions (Ld ≤200 μm) showed a strong relationship between ΔF and Ld (r = -0.898, p < 0.001), while there was a strong relationship between ΔL* and Ld in deeper lesions (Ld > 200 μm) (r = 0.858, p < 0.001). Our findings show that QLF system is a more efficient device for shallow early caries detection and that the spectrophotometer is a more stable device for the detection of deeper lesions.

Original languageEnglish
Pages (from-to)176-180
Number of pages5
JournalPhotodiagnosis and Photodynamic Therapy
Publication statusPublished - 2018 Sep

Bibliographical note

Funding Information:
This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (grant No. 2016R1D1A1B03934754 ) and a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) , funded by the Ministry of Health &Welfare, Republic of Korea (grant No. HI15C0889 ).

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Oncology
  • Dermatology
  • Pharmacology (medical)

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