Early Repolarization Pattern in Patients with Vasospastic Angina Is Related to Sudden Cardiac Death and Fatal Ventricular Arrhythmia

Chang Myung Oh, Jaewon Oh, Hye Jin Hwang, Jong Yun Kim, Hui Nam Pak, Moon Hyoung Lee, Boyoung Joung

Research output: Contribution to journalArticlepeer-review

Abstract

Background: This study was performed to investigate the prevalence and prognostic significance of early repolarization (ER) in patients with vasospastic angina (VA). Methods: We assessed the prevalence and prognostic significance of ER in 693 VA patients (age 51 ±9 years). The control group consisted of 1,189 age- and sex-matched healthy control. The primary end point was death from all causes, and secondary end points were aborted sudden cardiac death or fatal ventricular arrhythmia. Results: ER was more common in VA (36.9% [n=256]) than in control (5.5% [n=65], p<0.001). VA patients with ER (ER group) were more likely to be men (65% vs. 56%, p=0.017) than those without ER (Non-ER group). Although there was no difference in primary end point, secondary end points were more frequently observed as the initial presentation (2.7% vs. 0.7%, p=0.044), and during the mean follow up period of 86.7± 51.3 months (3.5% versus 0.9%, p=0.02) in the ER than in the non-ER group. A J-point elevation of more than 0.1 mV in the inferior leads was associated with an increased risk of secondary end points (HR 4.00,1.5210.55; p=0.005). Conclusion: ER was more frequently observed and associated with an increased risk of aborted sudden cardiac death or fatal ventricular arrhythmia in VA patients.

Original languageEnglish
Pages (from-to)423
Number of pages1
Journaljournal of arrhythmia
Volume27
Issue number4
DOIs
Publication statusPublished - 2011

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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