Effect of a new combined therapy with nano-carbonate apatite and CO 2 laser on dentin hypersensitivity in an in situ model

Sun Young Han, Ji Sun Kim, Young Seok Kim, Ho Keun Kwon, Baek Il Kim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objective: The aim of this study was to determine the occluding effects of a combination of dentifrice containing nano-carbonate apatite (n-CAP) and CO2 laser on dentinal tubules, and to evaluate the acid resistance of this combination after 4 days of treatment, by using an in situ model. Background data: The synergic effect of this combination was demonstrated in an in vitro study. Methods: This was a two period crossover, single-blind, randomized, four-treatment, split-mouth study. Ten healthy participants wore lower intraoral appliances during the treatment period. Specimens were divided into the following four groups: no treatment (control group), tooth-brushing using 20% n-CAP dentifrice (n-CAP group), CO2 laser irradiation (laser group), and laser irradiation after n-CAP application (combined group). Occluding effects were evaluated on 2 days (days 1 and 2), and then acid challenge was performed using grape juice on 2 days (days 3 and 4). All of the specimen surfaces were evaluated by a scanning electron microscope. Results: The combined group showed a better occluding effect than control group compared with other treatment groups, and this effect was 20% higher than that in the n-CAP group. Also, the combined group had the smallest open dentinal tubular area among all of the treatment groups. Conclusions: The combined therapy is a promising method for ensuring a long-lasting effect of dentin hypersensitivity treatment in clinical practice.

Original languageEnglish
Pages (from-to)394-400
Number of pages7
JournalPhotomedicine and laser surgery
Volume32
Issue number7
DOIs
Publication statusPublished - 2014 Jul 1

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Dentin Sensitivity
Apatite
Carbon Monoxide
Carbonates
Lasers
Laser beam effects
Dentifrices
Gas Lasers
Acid resistance
Therapeutics
Electron microscopes
Control Groups
Acids
Wear of materials
carboapatite
Vitis
Scanning
Mouth
Healthy Volunteers
Tooth

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

Cite this

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title = "Effect of a new combined therapy with nano-carbonate apatite and CO 2 laser on dentin hypersensitivity in an in situ model",
abstract = "Objective: The aim of this study was to determine the occluding effects of a combination of dentifrice containing nano-carbonate apatite (n-CAP) and CO2 laser on dentinal tubules, and to evaluate the acid resistance of this combination after 4 days of treatment, by using an in situ model. Background data: The synergic effect of this combination was demonstrated in an in vitro study. Methods: This was a two period crossover, single-blind, randomized, four-treatment, split-mouth study. Ten healthy participants wore lower intraoral appliances during the treatment period. Specimens were divided into the following four groups: no treatment (control group), tooth-brushing using 20{\%} n-CAP dentifrice (n-CAP group), CO2 laser irradiation (laser group), and laser irradiation after n-CAP application (combined group). Occluding effects were evaluated on 2 days (days 1 and 2), and then acid challenge was performed using grape juice on 2 days (days 3 and 4). All of the specimen surfaces were evaluated by a scanning electron microscope. Results: The combined group showed a better occluding effect than control group compared with other treatment groups, and this effect was 20{\%} higher than that in the n-CAP group. Also, the combined group had the smallest open dentinal tubular area among all of the treatment groups. Conclusions: The combined therapy is a promising method for ensuring a long-lasting effect of dentin hypersensitivity treatment in clinical practice.",
author = "Han, {Sun Young} and Kim, {Ji Sun} and Kim, {Young Seok} and Kwon, {Ho Keun} and Kim, {Baek Il}",
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Effect of a new combined therapy with nano-carbonate apatite and CO 2 laser on dentin hypersensitivity in an in situ model. / Han, Sun Young; Kim, Ji Sun; Kim, Young Seok; Kwon, Ho Keun; Kim, Baek Il.

In: Photomedicine and laser surgery, Vol. 32, No. 7, 01.07.2014, p. 394-400.

Research output: Contribution to journalArticle

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AU - Kim, Baek Il

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N2 - Objective: The aim of this study was to determine the occluding effects of a combination of dentifrice containing nano-carbonate apatite (n-CAP) and CO2 laser on dentinal tubules, and to evaluate the acid resistance of this combination after 4 days of treatment, by using an in situ model. Background data: The synergic effect of this combination was demonstrated in an in vitro study. Methods: This was a two period crossover, single-blind, randomized, four-treatment, split-mouth study. Ten healthy participants wore lower intraoral appliances during the treatment period. Specimens were divided into the following four groups: no treatment (control group), tooth-brushing using 20% n-CAP dentifrice (n-CAP group), CO2 laser irradiation (laser group), and laser irradiation after n-CAP application (combined group). Occluding effects were evaluated on 2 days (days 1 and 2), and then acid challenge was performed using grape juice on 2 days (days 3 and 4). All of the specimen surfaces were evaluated by a scanning electron microscope. Results: The combined group showed a better occluding effect than control group compared with other treatment groups, and this effect was 20% higher than that in the n-CAP group. Also, the combined group had the smallest open dentinal tubular area among all of the treatment groups. Conclusions: The combined therapy is a promising method for ensuring a long-lasting effect of dentin hypersensitivity treatment in clinical practice.

AB - Objective: The aim of this study was to determine the occluding effects of a combination of dentifrice containing nano-carbonate apatite (n-CAP) and CO2 laser on dentinal tubules, and to evaluate the acid resistance of this combination after 4 days of treatment, by using an in situ model. Background data: The synergic effect of this combination was demonstrated in an in vitro study. Methods: This was a two period crossover, single-blind, randomized, four-treatment, split-mouth study. Ten healthy participants wore lower intraoral appliances during the treatment period. Specimens were divided into the following four groups: no treatment (control group), tooth-brushing using 20% n-CAP dentifrice (n-CAP group), CO2 laser irradiation (laser group), and laser irradiation after n-CAP application (combined group). Occluding effects were evaluated on 2 days (days 1 and 2), and then acid challenge was performed using grape juice on 2 days (days 3 and 4). All of the specimen surfaces were evaluated by a scanning electron microscope. Results: The combined group showed a better occluding effect than control group compared with other treatment groups, and this effect was 20% higher than that in the n-CAP group. Also, the combined group had the smallest open dentinal tubular area among all of the treatment groups. Conclusions: The combined therapy is a promising method for ensuring a long-lasting effect of dentin hypersensitivity treatment in clinical practice.

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