Abstract
Background parenchymal enhancement (BPE) on breast magnetic resonance imaging (MRI) may either obscure or mimic malignancy. We evaluated the impact of BPE on the diagnostic performance of pre-operative MRI in breast cancer patients, and how second-look ultrasound (US) can help in guiding patient management. Two hundred fifty-three breast cancer patients with pre-operative MRI were included. In moderate or marked BPE, abnormal interpretation rate (38.9% vs. 12.2%) and biopsy rate (27.8% vs. 8.3%) were higher, and specificity (64.7% vs. 89.8%) was lower, compared with minimal or mild BPE (all p < 0.001). Visibility of MRI-detected additional suspicious lesions on second-look US did not differ between the two groups (86.7% in minimal or mild BPE vs. 77.1% in moderate or marked BPE, p = 0.296). Increased BPE was related to increased abnormal interpretation rate, additional biopsy rate and decreased specificity. Second-look US was useful in visualization of MRI-detected additional suspicious lesions, regardless of BPE.
| Original language | English |
|---|---|
| Pages (from-to) | 2766-2774 |
| Number of pages | 9 |
| Journal | Ultrasound in Medicine and Biology |
| Volume | 42 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 2016 Dec 1 |
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All Science Journal Classification (ASJC) codes
- Biophysics
- Radiological and Ultrasound Technology
- Acoustics and Ultrasonics
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Effect of Background Parenchymal Enhancement on Pre-Operative Breast Magnetic Resonance Imaging : How It Affects Interpretation and the Role of Second-Look Ultrasound in Patient Management. / Kim, Soo Yeon; Lee, Hye Sun; Kim, Eun Kyung; Kim, Min Jung; Moon, Hee Jung; Yoon, Jung Hyun.
In: Ultrasound in Medicine and Biology, Vol. 42, No. 12, 01.12.2016, p. 2766-2774.Research output: Contribution to journal › Article
TY - JOUR
T1 - Effect of Background Parenchymal Enhancement on Pre-Operative Breast Magnetic Resonance Imaging
T2 - How It Affects Interpretation and the Role of Second-Look Ultrasound in Patient Management
AU - Kim, Soo Yeon
AU - Lee, Hye Sun
AU - Kim, Eun Kyung
AU - Kim, Min Jung
AU - Moon, Hee Jung
AU - Yoon, Jung Hyun
PY - 2016/12/1
Y1 - 2016/12/1
N2 - Background parenchymal enhancement (BPE) on breast magnetic resonance imaging (MRI) may either obscure or mimic malignancy. We evaluated the impact of BPE on the diagnostic performance of pre-operative MRI in breast cancer patients, and how second-look ultrasound (US) can help in guiding patient management. Two hundred fifty-three breast cancer patients with pre-operative MRI were included. In moderate or marked BPE, abnormal interpretation rate (38.9% vs. 12.2%) and biopsy rate (27.8% vs. 8.3%) were higher, and specificity (64.7% vs. 89.8%) was lower, compared with minimal or mild BPE (all p < 0.001). Visibility of MRI-detected additional suspicious lesions on second-look US did not differ between the two groups (86.7% in minimal or mild BPE vs. 77.1% in moderate or marked BPE, p = 0.296). Increased BPE was related to increased abnormal interpretation rate, additional biopsy rate and decreased specificity. Second-look US was useful in visualization of MRI-detected additional suspicious lesions, regardless of BPE.
AB - Background parenchymal enhancement (BPE) on breast magnetic resonance imaging (MRI) may either obscure or mimic malignancy. We evaluated the impact of BPE on the diagnostic performance of pre-operative MRI in breast cancer patients, and how second-look ultrasound (US) can help in guiding patient management. Two hundred fifty-three breast cancer patients with pre-operative MRI were included. In moderate or marked BPE, abnormal interpretation rate (38.9% vs. 12.2%) and biopsy rate (27.8% vs. 8.3%) were higher, and specificity (64.7% vs. 89.8%) was lower, compared with minimal or mild BPE (all p < 0.001). Visibility of MRI-detected additional suspicious lesions on second-look US did not differ between the two groups (86.7% in minimal or mild BPE vs. 77.1% in moderate or marked BPE, p = 0.296). Increased BPE was related to increased abnormal interpretation rate, additional biopsy rate and decreased specificity. Second-look US was useful in visualization of MRI-detected additional suspicious lesions, regardless of BPE.
UR - http://www.scopus.com/inward/record.url?scp=84994756504&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84994756504&partnerID=8YFLogxK
U2 - 10.1016/j.ultrasmedbio.2016.08.008
DO - 10.1016/j.ultrasmedbio.2016.08.008
M3 - Article
C2 - 27658753
AN - SCOPUS:84994756504
VL - 42
SP - 2766
EP - 2774
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
SN - 0301-5629
IS - 12
ER -