Effect of baseline glomerular filtration rate on renal function following stenting for atherosclerotic renal artery stenosis

Jae Hyun Chang, Beom Seok Kim, Hyung Jung Oh, Tae Hyun Yoo, Shin Wook Kang, Ho Yung Lee, Donghoon Choi, Won Heum Shim, Kyu Hun Choi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objective. Percutaneous transluminal renal artery angioplasty and stenting (PTRAS) is one treatment option for atherosclerotic renal artery stenosis (ARAS). However, factors predicting the outcome remain controversial. This study investigated the effect of the baseline glomerular filtration rate (GFR) on renal function after PTRAS in patients with ARAS. Material and methods. Patients who underwent PTRAS due to significant ARAS (luminal narrowing ≥ 60%) were enrolled. The patients were divided into control (n = 57; estimated GFR (eGFR) ≥ 60 ml/min/1.73 m2) and chronic renal failure (CRF) groups (n = 53; eGFR <60 ml/min/1.73 m2), according to the baseline eGFR. Results. The mean age at the time of PTRAS was 62 ± 9 years, and the mean duration of follow-up was 50 ± 26 months. There was a significant decrease in eGFR after PTRAS in the control group, whereas the CRF group showed no significant change in eGFR. The percentage change in eGFR was negatively correlated with the baseline eGFR (r -0.274, p = 0.004). Multivariate linear regression revealed that only baseline eGFR predicted the change in eGFR (p = 0.032). Conclusions. PTRAS was more effective at preserving renal function in patients with moderately impaired renal function. Thus, baseline GFR may indicate the expected renal function outcome after PTRAS.

Original languageEnglish
Pages (from-to)169-174
Number of pages6
JournalScandinavian Journal of Urology and Nephrology
Volume44
Issue number3
DOIs
Publication statusPublished - 2010 Apr 24

All Science Journal Classification (ASJC) codes

  • Nephrology
  • Urology

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