Effect of core atom modification on photophysical properties and singlet oxygen generation efficiencies: Tetraphenylporphyrin analogues core-modified by oxygen and/or sulfur

Jeong Hyon Ha, Siwhan Ko, Chang Hee Lee, Won Young Lee, Yong Rok Kim

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Photophysical properties and singlet oxygen generation efficiencies of oxa- and/or thia-porphyrins have been investigated by time-resolved and steady-state spectroscopic methods. Introduction of sulfur atom into the porphyrin core induces a slight increment in the internal conversion rate and it also largely increases the intersystem crossing rate due to spin-orbit coupling enhancement, resulting the enhanced triplet state and singlet oxygen quantum yields. However, the quantum yields of mono oxygen-substituted porphyrin are reduced due to relatively more enhanced internal conversion. These suggest that sulfur modification in the core improves the photophysical efficiency of photosensitizers in the application respect of photodynamic therapy (PDT).

Original languageEnglish
Pages (from-to)271-278
Number of pages8
JournalChemical Physics Letters
Volume349
Issue number3-4
DOIs
Publication statusPublished - 2001 Nov 30

Fingerprint

Singlet Oxygen
Porphyrins
Sulfur
porphyrins
sulfur
internal conversion
Quantum yield
analogs
Oxygen
Atoms
oxygen
atoms
Photodynamic therapy
Photosensitizing Agents
atomic energy levels
therapy
Orbits
orbits
augmentation
tetraphenylporphyrin

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

Cite this

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abstract = "Photophysical properties and singlet oxygen generation efficiencies of oxa- and/or thia-porphyrins have been investigated by time-resolved and steady-state spectroscopic methods. Introduction of sulfur atom into the porphyrin core induces a slight increment in the internal conversion rate and it also largely increases the intersystem crossing rate due to spin-orbit coupling enhancement, resulting the enhanced triplet state and singlet oxygen quantum yields. However, the quantum yields of mono oxygen-substituted porphyrin are reduced due to relatively more enhanced internal conversion. These suggest that sulfur modification in the core improves the photophysical efficiency of photosensitizers in the application respect of photodynamic therapy (PDT).",
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Effect of core atom modification on photophysical properties and singlet oxygen generation efficiencies : Tetraphenylporphyrin analogues core-modified by oxygen and/or sulfur. / Ha, Jeong Hyon; Ko, Siwhan; Lee, Chang Hee; Lee, Won Young; Kim, Yong Rok.

In: Chemical Physics Letters, Vol. 349, No. 3-4, 30.11.2001, p. 271-278.

Research output: Contribution to journalArticle

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