Abstract
Objective To investigate the effect of previous incisional double-fold surgery on spontaneous resolution of eyelid retraction caused by Graves orbitopathy (GO) in Asian individuals. Design Retrospective review of medical records. Participants Patients (N = 30; 39 eyes) with eyelid retraction associated with GO with symptom duration of less than 6 months. Methods Patients who visited the Ophthalmology Department of Severance Hospital, Yonsei University, between January 2010 and December 2011, followed up for more than 6 months and in a euthyroid state with antithyroid drug treatment were included. Patients treated with steroids or who underwent surgery during follow-up were excluded. Upper scleral show was measured as the distance between the central upper lid margin and limbus at initial presentation and after 6 months. Comparative analysis was performed between the 2 groups delineated by history (n = 12; 16 eyes), or lack thereof (n = 18; 23 eyes), of incisional double-fold surgery before onset of GO symptoms and signs. Results Patient demographics and initial upper scleral show were not significantly different between groups. In both groups, upper scleral show significantly decreased at 6 months of follow-up (p < 0.001 in both groups); however, improvement of upper scleral show was significantly reduced in patients who had undergone previous double-fold surgery (0.8 ± 0.5 mm) than in nonsurgical patients (1.8 ± 0.5 mm; p < 0.001). Conclusions Graves eyelid retraction resolves spontaneously over time, albeit not completely. Previous double-fold surgery hinders the degree of spontaneous resolution, probably because of the fibrosis and cicatrization between the skin, the subcutaneous layer, and the levator complex.
| Original language | English |
|---|---|
| Pages (from-to) | 49-53 |
| Number of pages | 5 |
| Journal | Canadian Journal of Ophthalmology |
| Volume | 50 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2015 Feb 1 |
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All Science Journal Classification (ASJC) codes
- Ophthalmology
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Effect of double-fold surgery on spontaneous resolution of Graves' upper eyelid retraction. / Kim, Dong Kyu; Choi, Moonjung; Yoon, Jinsook.
In: Canadian Journal of Ophthalmology, Vol. 50, No. 1, 01.02.2015, p. 49-53.Research output: Contribution to journal › Article
TY - JOUR
T1 - Effect of double-fold surgery on spontaneous resolution of Graves' upper eyelid retraction
AU - Kim, Dong Kyu
AU - Choi, Moonjung
AU - Yoon, Jinsook
PY - 2015/2/1
Y1 - 2015/2/1
N2 - Objective To investigate the effect of previous incisional double-fold surgery on spontaneous resolution of eyelid retraction caused by Graves orbitopathy (GO) in Asian individuals. Design Retrospective review of medical records. Participants Patients (N = 30; 39 eyes) with eyelid retraction associated with GO with symptom duration of less than 6 months. Methods Patients who visited the Ophthalmology Department of Severance Hospital, Yonsei University, between January 2010 and December 2011, followed up for more than 6 months and in a euthyroid state with antithyroid drug treatment were included. Patients treated with steroids or who underwent surgery during follow-up were excluded. Upper scleral show was measured as the distance between the central upper lid margin and limbus at initial presentation and after 6 months. Comparative analysis was performed between the 2 groups delineated by history (n = 12; 16 eyes), or lack thereof (n = 18; 23 eyes), of incisional double-fold surgery before onset of GO symptoms and signs. Results Patient demographics and initial upper scleral show were not significantly different between groups. In both groups, upper scleral show significantly decreased at 6 months of follow-up (p < 0.001 in both groups); however, improvement of upper scleral show was significantly reduced in patients who had undergone previous double-fold surgery (0.8 ± 0.5 mm) than in nonsurgical patients (1.8 ± 0.5 mm; p < 0.001). Conclusions Graves eyelid retraction resolves spontaneously over time, albeit not completely. Previous double-fold surgery hinders the degree of spontaneous resolution, probably because of the fibrosis and cicatrization between the skin, the subcutaneous layer, and the levator complex.
AB - Objective To investigate the effect of previous incisional double-fold surgery on spontaneous resolution of eyelid retraction caused by Graves orbitopathy (GO) in Asian individuals. Design Retrospective review of medical records. Participants Patients (N = 30; 39 eyes) with eyelid retraction associated with GO with symptom duration of less than 6 months. Methods Patients who visited the Ophthalmology Department of Severance Hospital, Yonsei University, between January 2010 and December 2011, followed up for more than 6 months and in a euthyroid state with antithyroid drug treatment were included. Patients treated with steroids or who underwent surgery during follow-up were excluded. Upper scleral show was measured as the distance between the central upper lid margin and limbus at initial presentation and after 6 months. Comparative analysis was performed between the 2 groups delineated by history (n = 12; 16 eyes), or lack thereof (n = 18; 23 eyes), of incisional double-fold surgery before onset of GO symptoms and signs. Results Patient demographics and initial upper scleral show were not significantly different between groups. In both groups, upper scleral show significantly decreased at 6 months of follow-up (p < 0.001 in both groups); however, improvement of upper scleral show was significantly reduced in patients who had undergone previous double-fold surgery (0.8 ± 0.5 mm) than in nonsurgical patients (1.8 ± 0.5 mm; p < 0.001). Conclusions Graves eyelid retraction resolves spontaneously over time, albeit not completely. Previous double-fold surgery hinders the degree of spontaneous resolution, probably because of the fibrosis and cicatrization between the skin, the subcutaneous layer, and the levator complex.
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UR - http://www.scopus.com/inward/citedby.url?scp=84923028340&partnerID=8YFLogxK
U2 - 10.1016/j.jcjo.2014.08.012
DO - 10.1016/j.jcjo.2014.08.012
M3 - Article
C2 - 25677283
AN - SCOPUS:84923028340
VL - 50
SP - 49
EP - 53
JO - Canadian Journal of Ophthalmology
JF - Canadian Journal of Ophthalmology
SN - 0008-4182
IS - 1
ER -