Effect of other oxides on solubility and bioactivity in calcium phosphate glasses

M. C. Kim, K. N. Kim, K. M. Kim, S. H. Choi, C. K. Kim, R. Z. Legeros, Y. K. Lee

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The development of phosphate glasses for use in orthopaedic implants has attracted much interest because their chemical and physical properties make them suitable for use as bone-bonding materials. We prepared various compositions of CaO-P2O5-MO or CaO-P2O5-M 2O (M: K, Li, Na, Mg, Zn) glasses to measure ion release, solubility and bioactivity. The compositions with (Ca,M)/P molar ratio 0.6 were fixed P2O5 mol% content at 45.45 mol%, and varying MO or M 2O mol% at 10, 20 and 30 mol%. Ca2+ ion release properties were investigated in 0.1M potassium acetate with pH 6 at 37°C by immersing 50 mg of powder into 100 ml of acidic buffer solution. The highest and lowest extent of released Ca2+ ion was observed for composition with 10 mol% of K2O and 30 mol% of MgO, repectively. The weight loss in distilled water at 37°C was measured. Solubility increased with decreasing CaO content, but decreased with increasing MgO content. Bioactivity in the simulated body fluid at 37°C was measured.

Original languageEnglish
Pages (from-to)513-516
Number of pages4
JournalKey Engineering Materials
Volume284-286
DOIs
Publication statusPublished - 2005 Jan 1

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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