The development of phosphate glasses for use in orthopaedic implants has attracted much interest because their chemical and physical properties make them suitable for use as bone-bonding materials. We prepared various compositions of CaO-P2O5-MO or CaO-P2O5-M 2O (M: K, Li, Na, Mg, Zn) glasses to measure ion release, solubility and bioactivity. The compositions with (Ca,M)/P molar ratio 0.6 were fixed P2O5 mol% content at 45.45 mol%, and varying MO or M 2O mol% at 10, 20 and 30 mol%. Ca2+ ion release properties were investigated in 0.1M potassium acetate with pH 6 at 37°C by immersing 50 mg of powder into 100 ml of acidic buffer solution. The highest and lowest extent of released Ca2+ ion was observed for composition with 10 mol% of K2O and 30 mol% of MgO, repectively. The weight loss in distilled water at 37°C was measured. Solubility increased with decreasing CaO content, but decreased with increasing MgO content. Bioactivity in the simulated body fluid at 37°C was measured.
All Science Journal Classification (ASJC) codes
- Materials Science(all)
- Mechanics of Materials
- Mechanical Engineering