Background: Environmental factors can influence the pathogenesis of atopic dermatitis. In particular, a westernized residential environment that increases the density of house dust mites and gives rise to sick house syndrome could be a causative factor. Urushiol compounds extracted from Rhus verniciflua, a lacquer tree, have anti-insect and anti-microbial actions and reduce TVOC (total volatile organic compounds). Objective: The purpose of this study was to elucidate the effects of paint containing a novel polyurushiol synthesized from the extract of Rhus verniciflua on indoor air quality and atopic dermatitis patients. Methods: Nine patients with atopic dermatitis resistant to ordinary treatments were enrolled in this clinical trial. Patient rooms were painted with paint containing a novel polyurushiol extracted and synthesized from Rhus verniciflua. We measured TVOC before and after the painting. After a month, patients were evaluated with objective indices such as EASI score, serum IgE, eosinophil levels, and subjective satisfaction. Results: Seven of nine patients showed objective or subjective improvements of clinical symptoms, and TVOCs were reduced after painting. The questionnaire indicated that many patients felt an improvement in air quality. Conclusion: Painting with a novel polyurushiol synthesized from the extract of Rhus verniciflua could improve indoor air quality and atopic dermatitis.
|Number of pages||8|
|Journal||Korean Journal of Dermatology|
|Publication status||Published - 2010 Mar|
All Science Journal Classification (ASJC) codes