Effect of Prophylactic Brimonidine Instillation on Bleeding During Strabismus Surgery in Adults

Samin Hong, chanyun kim, Gong Je Seong, Sueng Han Han

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose: To investigate the effects of preoperative brimonidine-purite 0.15% instillation on intraoperative bleeding and postoperative subconjunctival hemorrhage during strabismus surgery in adult patients. Design: Randomized comparative interventional case series. Methods: One hundred and eighteen eyes of 90 consecutive adult patients were instilled with either a single drop of brimonidine-purite 0.15% (42 eyes), phenylephrine 1% (38 eyes), or sodium hyaluronate 0.1% (38 eyes) 15 minutes prior to strabismus surgery. Intraoperative bleeding and postoperative subconjunctival hemorrhage were graded on a scale of one to three. The scores were compared among the study groups. Results: Scores of the intraoperative bleeding and the postoperative subconjunctival hemorrhage of the treatment groups were significantly less than that of the control group (P < .001). The scores of the brimonidine group were similar to those of the phenylephrine group (intraoperative bleeding score, P = .405; subconjunctival hemorrhage score, P = .722). Conclusions: Topical brimonidine administration before strabismus surgery may reduce intraoperative bleeding and postoperative subconjunctival hemorrhage in adult patients.

Original languageEnglish
Pages (from-to)469-470
Number of pages2
JournalAmerican Journal of Ophthalmology
Volume144
Issue number3
DOIs
Publication statusPublished - 2007 Sep 1

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Strabismus
Postoperative Hemorrhage
Hemorrhage
Phenylephrine
Topical Administration
Hyaluronic Acid
Brimonidine Tartrate
Control Groups

All Science Journal Classification (ASJC) codes

  • Ophthalmology

Cite this

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abstract = "Purpose: To investigate the effects of preoperative brimonidine-purite 0.15{\%} instillation on intraoperative bleeding and postoperative subconjunctival hemorrhage during strabismus surgery in adult patients. Design: Randomized comparative interventional case series. Methods: One hundred and eighteen eyes of 90 consecutive adult patients were instilled with either a single drop of brimonidine-purite 0.15{\%} (42 eyes), phenylephrine 1{\%} (38 eyes), or sodium hyaluronate 0.1{\%} (38 eyes) 15 minutes prior to strabismus surgery. Intraoperative bleeding and postoperative subconjunctival hemorrhage were graded on a scale of one to three. The scores were compared among the study groups. Results: Scores of the intraoperative bleeding and the postoperative subconjunctival hemorrhage of the treatment groups were significantly less than that of the control group (P < .001). The scores of the brimonidine group were similar to those of the phenylephrine group (intraoperative bleeding score, P = .405; subconjunctival hemorrhage score, P = .722). Conclusions: Topical brimonidine administration before strabismus surgery may reduce intraoperative bleeding and postoperative subconjunctival hemorrhage in adult patients.",
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Effect of Prophylactic Brimonidine Instillation on Bleeding During Strabismus Surgery in Adults. / Hong, Samin; kim, chanyun; Seong, Gong Je; Han, Sueng Han.

In: American Journal of Ophthalmology, Vol. 144, No. 3, 01.09.2007, p. 469-470.

Research output: Contribution to journalArticle

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