Effect of vaccination with refined components of the organism on infection of mice with Mycobacterium leprae

Maeya Ngamying, Pathom Sawanpanyalert, Raywadee Butraporn, Junjira Nikasri, Sang Nae Cho, Louis Levy, Patrick J. Brennan

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Only native products of Mycobacterium leprae, whether cell wall, cytosol, or membrane derived, can confer protective immunity against challenge in the mouse footpad. Previously, recombinant proteins were shown to be ineffective. The cell wall skeleton - the mycolyl-arabinogalactan-peptidoglycan complex - devoid of proteins is not protective.

Original languageEnglish
Pages (from-to)1596-1598
Number of pages3
JournalInfection and Immunity
Volume71
Issue number3
DOIs
Publication statusPublished - 2003 Mar 1

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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