Only native products of Mycobacterium leprae, whether cell wall, cytosol, or membrane derived, can confer protective immunity against challenge in the mouse footpad. Previously, recombinant proteins were shown to be ineffective. The cell wall skeleton - the mycolyl-arabinogalactan-peptidoglycan complex - devoid of proteins is not protective.
All Science Journal Classification (ASJC) codes
- Infectious Diseases