Effectiveness of a culturally attuned Internet-based depression prevention program for Chinese adolescents: A randomized controlled trial

Patrick Ip, David Chim, Ko Ling Chan, Tim M.H. Li, Frederick Ka Wing Ho, Benjamin W. Van Voorhees, Agnes Tiwari, Anita Tsang, Charlie Wai Leung Chan, Matthew Ho, Winnie Tso, Wilfred Hing Sang Wong

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: Depression prevention among adolescents is crucial for reducing the global disease burden. Internet-based depression prevention approaches are found to be effective but they were mostly evaluated in a Western context. Grasping the Opportunity is a Chinese Internet intervention, which was translated and modified from CATCH-IT developed in the West. We aimed to evaluate the effectiveness of Grasp the Opportunity in reducing depressive symptoms in Chinese adolescents. Methods: In this randomized controlled trial, Chinese adolescents aged 13 to 17 years with mild-to-moderate depressive symptoms were recruited from three secondary schools in Hong Kong. The participants (n = 257) were randomly assigned to receive either intervention or attention control. The primary outcome was the improvement in depressive symptoms according to the revised Center for Epidemiologic Studies Depression Scale (CESD-R) at the 12-month follow-up. Analyses were performed using intention to treat (ITT). Results: The participants were randomly assigned to receive the intervention (n = 130) or attention control (n = 127). Follow-up data were obtained from 250 (97%) participants. Only 26 (10%) participants completed the intervention. Compared to the attention control, Grasp the Opportunity led to reductions in depressive symptoms at the 12-month follow-up with a medium effect size using ITT analysis (mean difference 2.6, 95% CI 0.59–5.55, effect size d = 0.36). Conclusions: Grasp the Opportunity is effective in reducing depressive symptoms in Chinese adolescents over a long follow-up period. Poor completion rate is the major challenge in the study.

Original languageEnglish
Pages (from-to)1123-1131
Number of pages9
JournalDepression and Anxiety
Volume33
Issue number12
DOIs
Publication statusPublished - 2016 Dec 1

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Internet
Randomized Controlled Trials
Depression
Hand Strength
Intention to Treat Analysis
Hong Kong
Epidemiologic Studies

All Science Journal Classification (ASJC) codes

  • Clinical Psychology
  • Psychiatry and Mental health

Cite this

Ip, P., Chim, D., Chan, K. L., Li, T. M. H., Ho, F. K. W., Van Voorhees, B. W., ... Wong, W. H. S. (2016). Effectiveness of a culturally attuned Internet-based depression prevention program for Chinese adolescents: A randomized controlled trial. Depression and Anxiety, 33(12), 1123-1131. https://doi.org/10.1002/da.22554
Ip, Patrick ; Chim, David ; Chan, Ko Ling ; Li, Tim M.H. ; Ho, Frederick Ka Wing ; Van Voorhees, Benjamin W. ; Tiwari, Agnes ; Tsang, Anita ; Chan, Charlie Wai Leung ; Ho, Matthew ; Tso, Winnie ; Wong, Wilfred Hing Sang. / Effectiveness of a culturally attuned Internet-based depression prevention program for Chinese adolescents : A randomized controlled trial. In: Depression and Anxiety. 2016 ; Vol. 33, No. 12. pp. 1123-1131.
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abstract = "Background: Depression prevention among adolescents is crucial for reducing the global disease burden. Internet-based depression prevention approaches are found to be effective but they were mostly evaluated in a Western context. Grasping the Opportunity is a Chinese Internet intervention, which was translated and modified from CATCH-IT developed in the West. We aimed to evaluate the effectiveness of Grasp the Opportunity in reducing depressive symptoms in Chinese adolescents. Methods: In this randomized controlled trial, Chinese adolescents aged 13 to 17 years with mild-to-moderate depressive symptoms were recruited from three secondary schools in Hong Kong. The participants (n = 257) were randomly assigned to receive either intervention or attention control. The primary outcome was the improvement in depressive symptoms according to the revised Center for Epidemiologic Studies Depression Scale (CESD-R) at the 12-month follow-up. Analyses were performed using intention to treat (ITT). Results: The participants were randomly assigned to receive the intervention (n = 130) or attention control (n = 127). Follow-up data were obtained from 250 (97{\%}) participants. Only 26 (10{\%}) participants completed the intervention. Compared to the attention control, Grasp the Opportunity led to reductions in depressive symptoms at the 12-month follow-up with a medium effect size using ITT analysis (mean difference 2.6, 95{\%} CI 0.59–5.55, effect size d = 0.36). Conclusions: Grasp the Opportunity is effective in reducing depressive symptoms in Chinese adolescents over a long follow-up period. Poor completion rate is the major challenge in the study.",
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Ip, P, Chim, D, Chan, KL, Li, TMH, Ho, FKW, Van Voorhees, BW, Tiwari, A, Tsang, A, Chan, CWL, Ho, M, Tso, W & Wong, WHS 2016, 'Effectiveness of a culturally attuned Internet-based depression prevention program for Chinese adolescents: A randomized controlled trial', Depression and Anxiety, vol. 33, no. 12, pp. 1123-1131. https://doi.org/10.1002/da.22554

Effectiveness of a culturally attuned Internet-based depression prevention program for Chinese adolescents : A randomized controlled trial. / Ip, Patrick; Chim, David; Chan, Ko Ling; Li, Tim M.H.; Ho, Frederick Ka Wing; Van Voorhees, Benjamin W.; Tiwari, Agnes; Tsang, Anita; Chan, Charlie Wai Leung; Ho, Matthew; Tso, Winnie; Wong, Wilfred Hing Sang.

In: Depression and Anxiety, Vol. 33, No. 12, 01.12.2016, p. 1123-1131.

Research output: Contribution to journalArticle

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T1 - Effectiveness of a culturally attuned Internet-based depression prevention program for Chinese adolescents

T2 - A randomized controlled trial

AU - Ip, Patrick

AU - Chim, David

AU - Chan, Ko Ling

AU - Li, Tim M.H.

AU - Ho, Frederick Ka Wing

AU - Van Voorhees, Benjamin W.

AU - Tiwari, Agnes

AU - Tsang, Anita

AU - Chan, Charlie Wai Leung

AU - Ho, Matthew

AU - Tso, Winnie

AU - Wong, Wilfred Hing Sang

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Background: Depression prevention among adolescents is crucial for reducing the global disease burden. Internet-based depression prevention approaches are found to be effective but they were mostly evaluated in a Western context. Grasping the Opportunity is a Chinese Internet intervention, which was translated and modified from CATCH-IT developed in the West. We aimed to evaluate the effectiveness of Grasp the Opportunity in reducing depressive symptoms in Chinese adolescents. Methods: In this randomized controlled trial, Chinese adolescents aged 13 to 17 years with mild-to-moderate depressive symptoms were recruited from three secondary schools in Hong Kong. The participants (n = 257) were randomly assigned to receive either intervention or attention control. The primary outcome was the improvement in depressive symptoms according to the revised Center for Epidemiologic Studies Depression Scale (CESD-R) at the 12-month follow-up. Analyses were performed using intention to treat (ITT). Results: The participants were randomly assigned to receive the intervention (n = 130) or attention control (n = 127). Follow-up data were obtained from 250 (97%) participants. Only 26 (10%) participants completed the intervention. Compared to the attention control, Grasp the Opportunity led to reductions in depressive symptoms at the 12-month follow-up with a medium effect size using ITT analysis (mean difference 2.6, 95% CI 0.59–5.55, effect size d = 0.36). Conclusions: Grasp the Opportunity is effective in reducing depressive symptoms in Chinese adolescents over a long follow-up period. Poor completion rate is the major challenge in the study.

AB - Background: Depression prevention among adolescents is crucial for reducing the global disease burden. Internet-based depression prevention approaches are found to be effective but they were mostly evaluated in a Western context. Grasping the Opportunity is a Chinese Internet intervention, which was translated and modified from CATCH-IT developed in the West. We aimed to evaluate the effectiveness of Grasp the Opportunity in reducing depressive symptoms in Chinese adolescents. Methods: In this randomized controlled trial, Chinese adolescents aged 13 to 17 years with mild-to-moderate depressive symptoms were recruited from three secondary schools in Hong Kong. The participants (n = 257) were randomly assigned to receive either intervention or attention control. The primary outcome was the improvement in depressive symptoms according to the revised Center for Epidemiologic Studies Depression Scale (CESD-R) at the 12-month follow-up. Analyses were performed using intention to treat (ITT). Results: The participants were randomly assigned to receive the intervention (n = 130) or attention control (n = 127). Follow-up data were obtained from 250 (97%) participants. Only 26 (10%) participants completed the intervention. Compared to the attention control, Grasp the Opportunity led to reductions in depressive symptoms at the 12-month follow-up with a medium effect size using ITT analysis (mean difference 2.6, 95% CI 0.59–5.55, effect size d = 0.36). Conclusions: Grasp the Opportunity is effective in reducing depressive symptoms in Chinese adolescents over a long follow-up period. Poor completion rate is the major challenge in the study.

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