Effects of chitosan nonwoven membrane on periodontal healing of surgically created one-wall intrabony defects in beagle dogs

Young Ju Yeo, Dong Won Jeon, ChangSung Kim, Seongho Choi, Kyoo Sung Cho, Yong Keun Lee, Chong Kwan Kim

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

The purpose of this study was to investigate the periodontal regenerative effects of a chitosan nonwoven membrane applied to surgically created preclinical one-wall intrabony defects in beagle dogs. One-wall intrabony defects (4 x 4 x 4 mm) were surgically created bilaterally in the mandibular second and fourth premolars of six beagle dogs. The surgical control group received a flap operation only. The resorbable-membrane (RM) group was treated with resorbable membrane. The chitosan-nonwoven-membrane (CNWM) group was treated with chitosan nonwoven membrane. The amount of junctional epithelium migration and the amount of connective tissue adhesion did not show any statistically significant differences among the groups. However, the amount of suprabony cementum regeneration, intrabony cementum regeneration, and alveolar bone regeneration showed significant differences (p < 0.05) between CNWM site group and control group. The results demonstrate the regenerative effects of the chitosan nonwoven membrane in one-wall intrabony defects of beagle dogs. The chitosan nonwoven membrane has the potential to support the cementum and bone regeneration, possibly by providing the conditions needed for guided tissue regeneration in the one-wall intrabony periodontal defects of beagle dogs.

Original languageEnglish
Pages (from-to)86-93
Number of pages8
JournalJournal of Biomedical Materials Research - Part B Applied Biomaterials
Volume72
Issue number1
DOIs
Publication statusPublished - 2005 Jan 15

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Chitosan
Membranes
Defects
Bone
Tissue regeneration
Adhesion
Tissue

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • Biomedical Engineering

Cite this

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abstract = "The purpose of this study was to investigate the periodontal regenerative effects of a chitosan nonwoven membrane applied to surgically created preclinical one-wall intrabony defects in beagle dogs. One-wall intrabony defects (4 x 4 x 4 mm) were surgically created bilaterally in the mandibular second and fourth premolars of six beagle dogs. The surgical control group received a flap operation only. The resorbable-membrane (RM) group was treated with resorbable membrane. The chitosan-nonwoven-membrane (CNWM) group was treated with chitosan nonwoven membrane. The amount of junctional epithelium migration and the amount of connective tissue adhesion did not show any statistically significant differences among the groups. However, the amount of suprabony cementum regeneration, intrabony cementum regeneration, and alveolar bone regeneration showed significant differences (p < 0.05) between CNWM site group and control group. The results demonstrate the regenerative effects of the chitosan nonwoven membrane in one-wall intrabony defects of beagle dogs. The chitosan nonwoven membrane has the potential to support the cementum and bone regeneration, possibly by providing the conditions needed for guided tissue regeneration in the one-wall intrabony periodontal defects of beagle dogs.",
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Effects of chitosan nonwoven membrane on periodontal healing of surgically created one-wall intrabony defects in beagle dogs. / Yeo, Young Ju; Jeon, Dong Won; Kim, ChangSung; Choi, Seongho; Cho, Kyoo Sung; Lee, Yong Keun; Kim, Chong Kwan.

In: Journal of Biomedical Materials Research - Part B Applied Biomaterials, Vol. 72, No. 1, 15.01.2005, p. 86-93.

Research output: Contribution to journalArticle

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