Effects of Coffee Intake on Incident Chronic Kidney Disease: A Community-Based Prospective Cohort Study

Jong Hyun Jhee, Ki Heon Nam, Seong Yeong An, Min Uk Cha, Misol Lee, Seohyun Park, Hyoungnae Kim, Hae Ryong Yun, Youn Kyung Kee, Jung Tak Park, Tae Ik Chang, Ea Wha Kang, Tae Hyun Yoo, Shin Wook Kang, Seung Hyeok Han

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Drinking coffee can raise public health problems, but the association between coffee and kidney disease is unknown. We studied whether coffee intake can affect the development of chronic kidney disease in the general population. Methods: We analyzed 8717 subjects with normal renal function recruited from the Korean Genome and Epidemiology Study (KoGES) cohort. Based on a food frequency questionnaire, coffee consumption was categorized into 5 groups: 0 per week, <1 cup per week, 1-6 cups per week, 1 cup per day, and ≥2 cups per day. The primary outcome was incident chronic kidney disease, defined as an estimated glomerular filtration rate <60 mL/min/1.73 m2. Results: The mean age (standard deviation) of study subjects was 52.0 (8.8) years, and 47.8% were male. Among the subjects, 52.8% were daily coffee consumers. During a mean follow-up of 11.3 (range, 5.9-11.5) years, 9.5% of participants developed chronic kidney disease. The incident chronic kidney disease occurred less in daily coffee consumers. Unadjusted hazard ratios (HRs) was significantly lower in daily coffee consumers. In multivariable Cox model even after adjustment of blood pressure, hypertension, cardiovascular disease, diabetes, and amount of daily intake for caffeine-containing foods such as tea and chocolate, coffee consumers with 1 cup per day (HR, 0.76; 95% confidence interval, 0.63-0.92) and ≥2 cups per day (HR, 0.80; 95% confidence interval, 0.65-0.98) were associated with a lower risk of chronic kidney disease development than nondrinkers. Time-averaged and time-varying Cox models yielded similar results. The rates of decline in glomerular filtration were lower in daily coffee consumers. Conclusions: Our findings suggest that daily coffee intake is associated with decreased risk of the development of chronic kidney disease.

Original languageEnglish
Pages (from-to)1482-1490.e3
JournalAmerican Journal of Medicine
Volume131
Issue number12
DOIs
Publication statusPublished - 2018 Dec

Fingerprint

Coffee
Chronic Renal Insufficiency
Cohort Studies
Prospective Studies
Proportional Hazards Models
Confidence Intervals
Food
Kidney Diseases
Tea
Caffeine
Glomerular Filtration Rate
Drinking
Epidemiology
Cardiovascular Diseases
Public Health
Genome
Blood Pressure
Hypertension
Kidney

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Jhee, Jong Hyun ; Nam, Ki Heon ; An, Seong Yeong ; Cha, Min Uk ; Lee, Misol ; Park, Seohyun ; Kim, Hyoungnae ; Yun, Hae Ryong ; Kee, Youn Kyung ; Park, Jung Tak ; Chang, Tae Ik ; Kang, Ea Wha ; Yoo, Tae Hyun ; Kang, Shin Wook ; Han, Seung Hyeok. / Effects of Coffee Intake on Incident Chronic Kidney Disease : A Community-Based Prospective Cohort Study. In: American Journal of Medicine. 2018 ; Vol. 131, No. 12. pp. 1482-1490.e3.
@article{9c66c14218844e658038246aafc7ceec,
title = "Effects of Coffee Intake on Incident Chronic Kidney Disease: A Community-Based Prospective Cohort Study",
abstract = "Background: Drinking coffee can raise public health problems, but the association between coffee and kidney disease is unknown. We studied whether coffee intake can affect the development of chronic kidney disease in the general population. Methods: We analyzed 8717 subjects with normal renal function recruited from the Korean Genome and Epidemiology Study (KoGES) cohort. Based on a food frequency questionnaire, coffee consumption was categorized into 5 groups: 0 per week, <1 cup per week, 1-6 cups per week, 1 cup per day, and ≥2 cups per day. The primary outcome was incident chronic kidney disease, defined as an estimated glomerular filtration rate <60 mL/min/1.73 m2. Results: The mean age (standard deviation) of study subjects was 52.0 (8.8) years, and 47.8{\%} were male. Among the subjects, 52.8{\%} were daily coffee consumers. During a mean follow-up of 11.3 (range, 5.9-11.5) years, 9.5{\%} of participants developed chronic kidney disease. The incident chronic kidney disease occurred less in daily coffee consumers. Unadjusted hazard ratios (HRs) was significantly lower in daily coffee consumers. In multivariable Cox model even after adjustment of blood pressure, hypertension, cardiovascular disease, diabetes, and amount of daily intake for caffeine-containing foods such as tea and chocolate, coffee consumers with 1 cup per day (HR, 0.76; 95{\%} confidence interval, 0.63-0.92) and ≥2 cups per day (HR, 0.80; 95{\%} confidence interval, 0.65-0.98) were associated with a lower risk of chronic kidney disease development than nondrinkers. Time-averaged and time-varying Cox models yielded similar results. The rates of decline in glomerular filtration were lower in daily coffee consumers. Conclusions: Our findings suggest that daily coffee intake is associated with decreased risk of the development of chronic kidney disease.",
author = "Jhee, {Jong Hyun} and Nam, {Ki Heon} and An, {Seong Yeong} and Cha, {Min Uk} and Misol Lee and Seohyun Park and Hyoungnae Kim and Yun, {Hae Ryong} and Kee, {Youn Kyung} and Park, {Jung Tak} and Chang, {Tae Ik} and Kang, {Ea Wha} and Yoo, {Tae Hyun} and Kang, {Shin Wook} and Han, {Seung Hyeok}",
year = "2018",
month = "12",
doi = "10.1016/j.amjmed.2018.05.021",
language = "English",
volume = "131",
pages = "1482--1490.e3",
journal = "American Journal of Medicine",
issn = "0002-9343",
publisher = "Elsevier Inc.",
number = "12",

}

Jhee, JH, Nam, KH, An, SY, Cha, MU, Lee, M, Park, S, Kim, H, Yun, HR, Kee, YK, Park, JT, Chang, TI, Kang, EW, Yoo, TH, Kang, SW & Han, SH 2018, 'Effects of Coffee Intake on Incident Chronic Kidney Disease: A Community-Based Prospective Cohort Study', American Journal of Medicine, vol. 131, no. 12, pp. 1482-1490.e3. https://doi.org/10.1016/j.amjmed.2018.05.021

Effects of Coffee Intake on Incident Chronic Kidney Disease : A Community-Based Prospective Cohort Study. / Jhee, Jong Hyun; Nam, Ki Heon; An, Seong Yeong; Cha, Min Uk; Lee, Misol; Park, Seohyun; Kim, Hyoungnae; Yun, Hae Ryong; Kee, Youn Kyung; Park, Jung Tak; Chang, Tae Ik; Kang, Ea Wha; Yoo, Tae Hyun; Kang, Shin Wook; Han, Seung Hyeok.

In: American Journal of Medicine, Vol. 131, No. 12, 12.2018, p. 1482-1490.e3.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Effects of Coffee Intake on Incident Chronic Kidney Disease

T2 - A Community-Based Prospective Cohort Study

AU - Jhee, Jong Hyun

AU - Nam, Ki Heon

AU - An, Seong Yeong

AU - Cha, Min Uk

AU - Lee, Misol

AU - Park, Seohyun

AU - Kim, Hyoungnae

AU - Yun, Hae Ryong

AU - Kee, Youn Kyung

AU - Park, Jung Tak

AU - Chang, Tae Ik

AU - Kang, Ea Wha

AU - Yoo, Tae Hyun

AU - Kang, Shin Wook

AU - Han, Seung Hyeok

PY - 2018/12

Y1 - 2018/12

N2 - Background: Drinking coffee can raise public health problems, but the association between coffee and kidney disease is unknown. We studied whether coffee intake can affect the development of chronic kidney disease in the general population. Methods: We analyzed 8717 subjects with normal renal function recruited from the Korean Genome and Epidemiology Study (KoGES) cohort. Based on a food frequency questionnaire, coffee consumption was categorized into 5 groups: 0 per week, <1 cup per week, 1-6 cups per week, 1 cup per day, and ≥2 cups per day. The primary outcome was incident chronic kidney disease, defined as an estimated glomerular filtration rate <60 mL/min/1.73 m2. Results: The mean age (standard deviation) of study subjects was 52.0 (8.8) years, and 47.8% were male. Among the subjects, 52.8% were daily coffee consumers. During a mean follow-up of 11.3 (range, 5.9-11.5) years, 9.5% of participants developed chronic kidney disease. The incident chronic kidney disease occurred less in daily coffee consumers. Unadjusted hazard ratios (HRs) was significantly lower in daily coffee consumers. In multivariable Cox model even after adjustment of blood pressure, hypertension, cardiovascular disease, diabetes, and amount of daily intake for caffeine-containing foods such as tea and chocolate, coffee consumers with 1 cup per day (HR, 0.76; 95% confidence interval, 0.63-0.92) and ≥2 cups per day (HR, 0.80; 95% confidence interval, 0.65-0.98) were associated with a lower risk of chronic kidney disease development than nondrinkers. Time-averaged and time-varying Cox models yielded similar results. The rates of decline in glomerular filtration were lower in daily coffee consumers. Conclusions: Our findings suggest that daily coffee intake is associated with decreased risk of the development of chronic kidney disease.

AB - Background: Drinking coffee can raise public health problems, but the association between coffee and kidney disease is unknown. We studied whether coffee intake can affect the development of chronic kidney disease in the general population. Methods: We analyzed 8717 subjects with normal renal function recruited from the Korean Genome and Epidemiology Study (KoGES) cohort. Based on a food frequency questionnaire, coffee consumption was categorized into 5 groups: 0 per week, <1 cup per week, 1-6 cups per week, 1 cup per day, and ≥2 cups per day. The primary outcome was incident chronic kidney disease, defined as an estimated glomerular filtration rate <60 mL/min/1.73 m2. Results: The mean age (standard deviation) of study subjects was 52.0 (8.8) years, and 47.8% were male. Among the subjects, 52.8% were daily coffee consumers. During a mean follow-up of 11.3 (range, 5.9-11.5) years, 9.5% of participants developed chronic kidney disease. The incident chronic kidney disease occurred less in daily coffee consumers. Unadjusted hazard ratios (HRs) was significantly lower in daily coffee consumers. In multivariable Cox model even after adjustment of blood pressure, hypertension, cardiovascular disease, diabetes, and amount of daily intake for caffeine-containing foods such as tea and chocolate, coffee consumers with 1 cup per day (HR, 0.76; 95% confidence interval, 0.63-0.92) and ≥2 cups per day (HR, 0.80; 95% confidence interval, 0.65-0.98) were associated with a lower risk of chronic kidney disease development than nondrinkers. Time-averaged and time-varying Cox models yielded similar results. The rates of decline in glomerular filtration were lower in daily coffee consumers. Conclusions: Our findings suggest that daily coffee intake is associated with decreased risk of the development of chronic kidney disease.

UR - http://www.scopus.com/inward/record.url?scp=85049104750&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85049104750&partnerID=8YFLogxK

U2 - 10.1016/j.amjmed.2018.05.021

DO - 10.1016/j.amjmed.2018.05.021

M3 - Article

C2 - 29906428

AN - SCOPUS:85049104750

VL - 131

SP - 1482-1490.e3

JO - American Journal of Medicine

JF - American Journal of Medicine

SN - 0002-9343

IS - 12

ER -